Cryo-EM Structure of a Possum Enterovirus.

Ivy Wang, Sandeep K Gupta, Guillaume Ems, Nadishka Jayawardena, Mike Strauss, Mihnea Bostina

Abstract read

In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivy WangDepartment of Anatomy and Cell Biology, McGill University, Montreal, QC H3A 0C7, Canada.

Sandeep K GuptaAgResearch, Palmerston North 4442, New Zealand.ORCID 0000-0002-9746-0075

Guillaume EmsDepartment of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand.ORCID 0000-0002-8968-1759

Nadishka JayawardenaDepartment of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand.

Mike StraussDepartment of Anatomy and Cell Biology, McGill University, Montreal, QC H3A 0C7, Canada.ORCID 0000-0002-0986-2868

Mihnea BostinaDepartment of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand.ORCID 0000-0003-3621-3772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses (EVs) represent a substantial concern to global health. Here, we present the cryo-EM structure of a non-human enterovirus, EV-F4, isolated from the Australian brushtail possum to assess the structural diversity of these picornaviruses. The capsid structure, determined to ~3 Å resolution by single particle analysis, exhibits a largely smooth surface, similar to EV-F3 (formerly BEV-2). Although the cellular receptor is not known, the absence of charged residues on the outer surface of the canyon suggest a different receptor type than for EV-F3. Density for the pocket factor is clear, with the entrance to the pocket being smaller than for other enteroviruses.

Indexed as

AnimalsAustraliaCapsidCryoelectron MicroscopyEnterovirusEnterovirus InfectionsTrichosuruscapsid structurecryo-electron microscopyenteroviruspossum

Identifiers

PMID35215909

DOI10.3390/v14020318

PMCPMC8879876

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.