Evidence map›Paper›PMID 35215896›Full record

ArticleViruses2022

Community-Based Screening for Hepatitis B and C Infectivity Using Two Quantitative Antigens to Identify Endemic Townships.

Wei-Cheng Huang, Yu-Chen Lin, Po-Ju Chen, Nien-Tzu Hsu, Chia-Ling Tu, Te-Sheng Chang, Chao-Hung Hung, Kwong-Ming Kee, Wen-Hua Chao, Sheng-Nan Lu

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wei-Cheng HuangDepartment of Geriatric, Chang Gung Memorial Hospital Chiayi Branch, Puzi 61363, Taiwan.
Yu-Chen LinChiayi County Health Bureau, Taibao 60044, Taiwan.
Po-Ju ChenDepartment of Family Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833253, Taiwan.ORCID 0000-0003-1204-3027
Nien-Tzu HsuBiostatistics Center, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833253, Taiwan.
Chia-Ling TuDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Chiayi Branch, Puzi 61363, Taiwan.
Te-Sheng ChangDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Chiayi Branch, Puzi 61363, Taiwan.ORCID 0000-0002-1581-6948
Chao-Hung HungCollege of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.
Kwong-Ming KeeCollege of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.ORCID 0000-0003-4836-4252
Wen-Hua ChaoChiayi County Health Bureau, Taibao 60044, Taiwan.
Sheng-Nan LuCollege of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.
Chang Gung University · TWKaohsiung Chang Gung Memorial Hospital · TWChanghua County Public Health Bureau · TWChiayi Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Screening and linkage to care are essential to achieve viral hepatitis elimination before 2030. The accurate identification of endemic areas is important for controlling diseases with geographic aggregation. Viral activity drives prognosis of chronic hepatitis B and hepatitis C virus infection. This screening was conducted in Chiayi County from 2018-2019. All residents aged 30 years or older were invited to participate in quantitative HBsAg (qHBsAg) and HCV Ag screening. Among the 4010 participants (male:female = 1630:2380), the prevalence of qHBsAg and HCV Ag was 9.9% (396/4010) and 4.1% (163/4010), respectively. High-prevalence townships were identified, three for qHBsAg > 15% and two for HCV Ag > 10%. The age-specific prevalence of qHBsAg was distributed in an inverse U-shape with a peak (16.0%, 68/424) for subjects in their 40 s; for HCV, prevalence increased with age. Concentrations of qHBsAg < 200 IU/mL were found in 54% (214/396) of carriers. The rate of oral antiviral treatment for HCV was 75.5% (114/151), with subjects younger than 75 years tending to undergo treatment (85.6% vs. 57.4%,

Indexed as

AdultAgedAged, 80 and overAntiviral AgentsDNA, ViralFemaleHepacivirusHepatitis AntigensHepatitis BHepatitis B virusHepatitis CHumansMaleMass ScreeningMiddle AgedPrevalenceAntiviral AgentsDNA, ViralHepatitis Antigenseliminationendemichepatitis C core antigenhepatitis C virusquantitative HBsAg

Identifiers

PMID35215896
PMCPMC8879708
OpenAlexW4210769692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.