Evidence map›Paper›PMID 35215837›Full record

ArticleViruses2022

Seroepidemiological Survey of West Nile Virus Infections in Horses from Berlin/Brandenburg and North Rhine-Westphalia, Germany.

Felicitas Bergmann, Dagmar S Trachsel, Sabita D Stoeckle, Joke Bernis Sierra, Stephan Lübke, Martin H Groschup, Heidrun Gehlen, Ute Ziegler

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Felicitas BergmannFriedrich-Loeffler Institut, Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-8338-2961
Dagmar S TrachselDepartment of Veterinary Medicine, Equine Clinic, Internal Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0001-5103-8402
Sabita D StoeckleDepartment of Veterinary Medicine, Equine Clinic, Internal Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
Joke Bernis SierraEquine Veterinary Practice, 53819 Neunkirchen-Seelscheid, Germany.
Stephan LübkeEquine Veterinary Practice, 53819 Neunkirchen-Seelscheid, Germany.
Martin H GroschupFriedrich-Loeffler Institut, Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0003-0215-185X
Heidrun GehlenDepartment of Veterinary Medicine, Equine Clinic, Internal Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0001-5451-4232
Ute ZieglerFriedrich-Loeffler Institut, Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-5295-7339
Freie Universität Berlin · DEFriedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the introduction of the West Nile virus (WNV) into eastern Germany in 2018, increasing infections have been diagnosed in birds, equines, and humans over time, while the spread of WNV into western Germany remained unclear. We screened 437 equine sera from 2018 to 2020, excluding vaccinated horses, collected from convenience sampled patients in the eastern and western parts of Germany, for WNV-specific antibodies (ELISAs followed by virus/specific neutralization tests) and genomes (RT-qPCRs). Clinical presentations, final diagnoses, and demographic data were also recorded. In the eastern part, a total of eight horses were found WNV seropositive in 2019 (seroprevalence of 8.16%) and 27 in 2020 (13.77%). There were also two clinically unsuspected horses with WNV-specific antibodies in the western part from 2020 (2.63%), albeit travel history-related infections could not be excluded. None of the horse sera contained WNV-specific genomes. Eight horses in eastern Germany carried WNV-IgM antibodies, but only four of these showed typical clinical signs. These results underline the difficulty of detecting a WNV infection in a horse solely based on clinical signs. Thus, WNV circulation is established in the horse population in eastern Germany, but not yet in the western part.

Indexed as

Age FactorsAnimalsAntibodies, ViralBerlinEnzyme-Linked Immunosorbent AssayFemaleGermanyHorse DiseasesHorsesImmunoglobulin MMaleSeroepidemiologic StudiesWest Nile FeverWest Nile virusAntibodies, ViralImmunoglobulin MGermanyhorsesseroepidemiologicalseroprevalenceWest Nile virus

Identifiers

PMID35215837
PMCPMC8877243
OpenAlexW4210682376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.