Evidence map›Paper›PMID 35215825›Full record

ReviewViruses2022

Vectorial Release of Human RNA Viruses from Epithelial Cells.

Sabine Chapuy-Regaud, Claire Allioux, Nicolas Capelli, Marion Migueres, Sébastien Lhomme, Jacques Izopet

Abstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sabine Chapuy-RegaudDepartment of Virology, CHU Purpan, F-31059 Toulouse, France.
Claire AlliouxINFINITy (Toulouse Institute for Infectious and Inflammatory Diseases), INSERM UMR1291, CNRS UMR5051, Université Toulouse III, CHU Purpan, F-31024 Toulouse, France.ORCID 0000-0003-3011-0094
Nicolas CapelliDepartment of Virology, CHU Purpan, F-31059 Toulouse, France.
Marion MigueresDepartment of Virology, CHU Purpan, F-31059 Toulouse, France.ORCID 0000-0001-7791-3201
Sébastien LhommeDepartment of Virology, CHU Purpan, F-31059 Toulouse, France.ORCID 0000-0001-7908-1576
Jacques IzopetDepartment of Virology, CHU Purpan, F-31059 Toulouse, France.ORCID 0000-0002-8462-3234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial cells are apico-basolateral polarized cells that line all tubular organs and are often targets for infectious agents. This review focuses on the release of human RNA virus particles from both sides of polarized human cells grown on transwells. Most viruses that infect the mucosa leave their host cells mainly via the apical side while basolateral release is linked to virus propagation within the host. Viruses do this by hijacking the cellular factors involved in polarization and trafficking. Thus, understanding epithelial polarization is essential for a clear understanding of virus pathophysiology.

Indexed as

Virus ReleaseCell PolarityEpithelial CellsHumansRNA VirusesVirionVirus AssemblyVirus Replicationepitheliumhuman RNA viruspolarizationrelease or egress

Identifiers

PMID35215825
PMCPMC8875463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.