Evidence map›Paper›PMID 35215813›Full record

ArticleViruses2022

Hyperendemic Dengue and Possible Zika Circulation in the Westernmost Region of the Indonesian Archipelago.

Harapan Harapan, Kritu Panta, Alice Michie, Timo Ernst, Suzi McCarthy, Muhsin Muhsin, Safarianti Safarianti, Tjut Mariam Zanaria, Mudatsir Mudatsir, R Tedjo Sasmono and 1 more

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Harapan HarapanMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.ORCID 0000-0001-7630-8413
Kritu PantaSchool of Biomedical Sciences, University of Western Australia, Nedlands, WA 6009, Australia.
Alice MichieSchool of Biomedical Sciences, University of Western Australia, Nedlands, WA 6009, Australia.
Timo ErnstSchool of Biomedical Sciences, University of Western Australia, Nedlands, WA 6009, Australia.
Suzi McCarthySchool of Biomedical Sciences, University of Western Australia, Nedlands, WA 6009, Australia.
Muhsin MuhsinDepartment of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.ORCID 0000-0003-4357-5536
Safarianti SafariantiDepartment of Parasitology, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
Tjut Mariam ZanariaDepartment of Parasitology, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
Mudatsir MudatsirMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.ORCID 0000-0002-5643-9384
R Tedjo SasmonoEijkman Institute for Molecular Biology, Jakarta 10430, Indonesia.ORCID 0000-0003-0986-2590
Allison ImrieSchool of Biomedical Sciences, University of Western Australia, Nedlands, WA 6009, Australia.ORCID 0000-0003-4715-6662

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transmission of dengue and other medically important mosquito-borne viruses in the westernmost region of Indonesia is not well described. We assessed dengue and Zika virus seroprevalence in Aceh province, the westernmost area of the Indonesian archipelago. Serum samples collected from 199 randomly sampled healthy residents of Aceh Jaya in 2017 were analyzed for neutralizing antibodies by plaque reduction neutralization test (PRNT). Almost all study participants (198/199; 99.5%) presented with multitypic profiles of neutralizing antibodies to two or more DENV serotypes, indicating transmission of multiple DENV in the region prior to 2017. All residents were exposed to one or more DENV serotypes by the age of 30 years. The highest geometric mean titers were measured for DENV-4, followed by DENV-1, DENV-2 and DENV-3. Among a subset of 116 sera, 27 neutralized ZIKV with a high stringency (20 with PRNT

Indexed as

AdolescentAdultAgedAntibodies, ViralChildChild, PreschoolDengueDengue VirusFemaleHumansIndonesiaMaleMiddle AgedNeutralization TestsSeroepidemiologic StudiesYoung AdultAntibodies, ViralAcehdengueIndonesiaPRNTseroprevalenceZika

Identifiers

PMID35215813
PMCPMC8875625

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.