Evidence map›Paper›PMID 35215676›Full record

ArticlePolymers2022

Development of 3D Printed Biodegradable Mesh with Antimicrobial Properties for Pelvic Organ Prolapse.

Jiongyu Ren, Rebecca Murray, Cynthia S Wong, Jilong Qin, Michael Chen, Makrina Totsika, Andrew D Riddell, Andrea Warwick, Nicholas Rukin, Maria A Woodruff

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  7. Review
  8. Article
  9. Article
  10. Rising role of 3D-printing in delivery of therapeutics for infectious disease.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  11. Article
  12. A novel degradable PCL/PLLA strapping band for internal fixation of fracture.Journal of materials science. Materials in medicine · 2023
    Article
  13. Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023
    Article
  14. Tissue-engineered repair material for pelvic floor dysfunction.Frontiers in bioengineering and biotechnology · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jiongyu RenCentre for Biomedical Technologies, Queensland University of Technology (QUT), Brisbane, QLD 4000, Australia.ORCID 0000-0001-5661-5723
Rebecca MurrayHerston Biofabrication Institute, Metro North Health, Brisbane, QLD 4029, Australia.
Cynthia S WongAikenhead Centre for Medical Discovery (ACMD), St Vincent's Hospital, Melbourne, VIC 3065, Australia.ORCID 0000-0003-3576-1232
Jilong QinCentre for Immunology and Infection Control, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4000, Australia.ORCID 0000-0002-5867-6332
Michael ChenCentre for Biomedical Technologies, Queensland University of Technology (QUT), Brisbane, QLD 4000, Australia.
Makrina TotsikaCentre for Immunology and Infection Control, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4000, Australia.ORCID 0000-0003-2468-0293
Andrew D RiddellRedcliffe Hospital, Metro North Health, Redcliffe, QLD 4020, Australia.
Andrea WarwickRedcliffe Hospital, Metro North Health, Redcliffe, QLD 4020, Australia.
Nicholas RukinHerston Biofabrication Institute, Metro North Health, Brisbane, QLD 4029, Australia.
Maria A WoodruffCentre for Biomedical Technologies, Queensland University of Technology (QUT), Brisbane, QLD 4000, Australia.
Queensland University of Technology · AUQueensland Health · AURedcliffe Hospital · AUSt Vincent's Hospital Melbourne · AUThe University of Queensland · AU

Funding

Metro North Hospital and Health Services; Queensland University of Technology CRG 172-2019
6 · The paper itself

Abstract

To address the increasing demand for safe and effective treatment options for pelvic organ prolapse (POP) due to the worldwide ban of the traditional polypropylene meshes, this study introduced degradable polycaprolactone (PCL)/polyethylene glycol (PEG) composite meshes fabricated with melt-electrowriting (MEW). Two PCL/PEG mesh groups: 90:10 and 75:25 (PCL:PEG, wt%) were fabricated and characterized for their degradation rate and mechanical properties, with PCL meshes used as a control. The PCL/PEG composites showed controllable degradation rates by adjusting the PEG content and produced mechanical properties, such as maximal forces, that were higher than PCL alone. The antibacterial properties of the meshes were elicited by coating them with a commonly used antibiotic: azithromycin. Two dosage levels were used for the coating: 0.5 mg and 1 mg per mesh, and both dosage levels were found to be effective in suppressing the growth of

Indexed as

antibacterialbiocompatiblecontrollable degradation ratepelvic organ prolapsepolycaprolactonepolyethylene glycol

Identifiers

PMID35215676
PMCPMC8877663
OpenAlexW4213118871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.