Trial reportNutrients2022
Maternal Hemoglobin Concentrations and Birth Weight, Low Birth Weight (LBW), and Small for Gestational Age (SGA): Findings from a Prospective Study in Northwest China.
Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Daily oral iron supplementation during pregnancy.The Cochrane database of systematic reviews · 2024Pooled it
- Haemoglobin Concentrations and Maternal and Neonatal Outcomes: Identifying Optimal Haemoglobin Ranges.Paediatric and perinatal epidemiology · 2026Article
- Article
- Association of maternal longitudinal haemoglobin concentrations with adverse pregnancy outcomes: A prospective cohort study.Journal of global health · 2026Observational
- Association of maternal hemoglobin levels and chorioamnionitis with preterm birth and low birth weight: a cohort study.World journal of pediatrics : WJP · 2026Article
- Prevalence, risk factors, and adverse maternal and fetal outcomes of anemia during pregnancy: a retrospective study in China, 2012-2020.BMC pregnancy and childbirth · 2026Article
- Associations of maternal hemoglobin and its changes with gestational diabetes mellitus: a prospective cohort study.Nutrition journal · 2026Article
- Gestational Weight Gain and Different Degrees of Preterm Birth: A Hospital-Based Study in Chinese Singleton Pregnancies.Nursing open · 2025Observational
- Article
- Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, ColombiaBiomedica : revista del Instituto Nacional de Salud · 2025Article
- Prenatal Hemoglobin Concentration and Long-Term Child Neurocognitive Development.The American journal of tropical medicine and hygiene · 2025Article
- Relationships between hemoglobin levels at admission and adverse maternal and perinatal outcomes in patients with preeclampsia.PloS one · 2025Article
- Analysis of clinical risk factors of premature infants in Chinese women based on anemia status.Frontiers in pediatrics · 2025Article
- Association between maternal haemoglobin status during pregnancy and children's mental and psychomotor development at 18 months of age: Evidence from rural Bangladesh.Global health action · 2024Article
- Integrated proteomic and transcriptomic landscape of human placenta in small for gestational age infants.iScience · 2024Article
- Association between gestational arsenic exposure and infant physical development: a prospective cohort study.BMC public health · 2024Article
- Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy.Cureus · 2024Article
- Maternal anaemia during early pregnancy and the risk of neonatal outcomes: a prospective cohort study in Central China.BMJ paediatrics open · 2024Article
- Article
- Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Birth weight and related outcomes have profound influences on life cycle health, but the effect of maternal hemoglobin concentration during pregnancy on birth weight is still unclear. This study aims to reveal the associations between maternal hemoglobin concentrations in different trimesters of pregnancy and neonatal birth weight, LBW, and SGA. This was a prospective study based on a cluster-randomized controlled trial conducted from July 2015 to December 2019 in rural areas of Northwest China. Information on maternal socio-demographic status, health-related factors, antenatal visits, and neonatal birth outcomes were collected. A total of 3748 women and their babies were included in the final analysis. A total of 65.1% and 46.3% of the participants had anemia or hemoglobin ≥ 130 g/L during pregnancy. In the third trimester, maternal hemoglobin concentration was associated with birth weight in an inverted U-shaped curve and with the risks of LBW and SGA in extended U-shaped curves. The relatively higher birth weight and lower risks for LBW and SGA were observed when hemoglobin concentration was 100-110 g/L. When maternal hemoglobin was <70 g/L or >130 g/L, the neonatal birth weight was more than 100 g lower than that when the maternal hemoglobin was 100 g/L. In conclusion, both low and high hemoglobin concentrations in the third trimester could be adverse to fetal weight growth and increase the risks of LBW and SGA, respectively. In addition to severe anemia, maternal hemoglobin >130 g/L in the third trimester should be paid great attention to in the practice of maternal and child health care.
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