Evidence map›Paper›PMID 35215411›Full record

ArticleNutrients2022

Beneficial Effects of Partly Milled Highland Barley on the Prevention of High-Fat Diet-Induced Glycometabolic Disorder and the Modulation of Gut Microbiota in Mice.

Siqi Li, Mengqian Wang, Chang Li, Qingjia Meng, Yantong Meng, Jian Ying, Shuqun Bai, Qun Shen, Yong Xue

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Effect of Resveratrol on the intestinal microbiota in Type2 diabetes Mellitus mice.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. [Adaptive Regulation of Glucose Metabolism and Diseases in High-Altitude Areas].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Anti-Obesity Activity ofNutrients · 2024
    Article
  14. Article
  15. Diet-Induced Gut Dysbiosis and Leaky Gut Syndrome.Journal of microbiology and biotechnology · 2024
    Review
  16. Article
  17. Molecules (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siqi LiNational Engineering and Technology Research Center for Fruits and Vegetables, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.ORCID 0000-0001-8572-6166
Mengqian WangCOFCO Nutrition and Health Research Institute Co., Ltd., Beijing 102209, China.ORCID 0000-0002-5378-9098
Chang LiNational Engineering and Technology Research Center for Fruits and Vegetables, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Qingjia MengCOFCO Nutrition and Health Research Institute Co., Ltd., Beijing 102209, China.ORCID 0000-0003-2847-2221
Yantong MengNational Engineering and Technology Research Center for Fruits and Vegetables, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Jian YingCOFCO Nutrition and Health Research Institute Co., Ltd., Beijing 102209, China.ORCID 0000-0002-9582-0065
Shuqun BaiCOFCO Nutrition and Health Research Institute Co., Ltd., Beijing 102209, China.
Qun ShenNational Center of Technology Innovation (Deep Processing of Highland Barley) in Food Industry, China Agricultural University, No. 17 Qinghua East Road, Haidian District, Beijing 100083, China.ORCID 0000-0002-2154-6104
Yong XueNational Engineering and Technology Research Center for Fruits and Vegetables, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.

Funding

China key research and development program No. 2018YFE0206300-02Food processing industry of highland barley in Tibet-COFCO Key Research and Development Project (2019)National Natural Science Foundation of China No. 81803234Xinghua Industrial Research Centre for Food Science and Human Health, China Agricultural University
6 · The paper itself

Abstract

The nutritional functions of highland barley (HB) are superior to those of regular cereals and have attracted increasing attention in recent years. The objective of this study was to investigate whether partly milled highland barley (PHB) can regulate the serum glucose and lipid disorders of mice fed a high-fat diet (HFD) and to further explore their potential gut microbiota modulatory effect. Our results showed that PHB supplementation significantly reduced fasting blood glucose (FBG) and improved oral glucose tolerance. Histological observations confirmed the ability of PHB to alleviate liver and intestine damage. Furthermore, the results of 16S amplicon sequencing revealed that PHB prevented a HFD-induced gut microbiota dysbiosis, enriching some beneficial bacteria, such as

Indexed as

Gastrointestinal MicrobiomeHordeumAnimalsDiet, High-FatDysbiosisMiceMice, Inbred C57BLgut microbiotahighland barleyinsulin resistanceobesity

Identifiers

PMID35215411
PMCPMC8877997

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.