Evidence map›Paper›PMID 35215339›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Design, Molecular Docking, Synthesis, Anticancer and Anti-Hyperglycemic Assessments of Thiazolidine-2,4-diones Bearing Sulfonylthiourea Moieties as Potent VEGFR-2 Inhibitors and PPARγ Agonists.

Mohamed A Abdelgawad, Khaled El-Adl, Sanadelaslam S A El-Hddad, Mostafa M Elhady, Nashwa M Saleh, Mohamed M Khalifa, Fathalla Khedr, Mohamed Alswah, AbdElAziz A Nayl, Mohammed M Ghoneim and 1 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Rationale,RSC advances · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Design, synthesis,RSC advances · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. (Molecules (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohamed A AbdelgawadDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0001-9035-5638
Khaled El-AdlPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.
Sanadelaslam S A El-HddadPharmaceutical Chemistry Department, Faculty of Pharmacy, Omar Almukhtar University, Al Bayda 991, Libya.ORCID 0000-0002-7183-6505
Mostafa M ElhadyDepartment of Biochemistry, Faculty of Science, Ain Shams University, Abbassia, Cairo 11566, Egypt.
Nashwa M SalehDepartment of Chemistry, Faculty of Science, Al-Azhar University (Girls Branch), Cairo 11754, Egypt.
Mohamed M KhalifaPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-8146-993X
Fathalla KhedrPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.
Mohamed AlswahPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo 11884, Egypt.
AbdElAziz A NaylDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-0531-5194
Mohammed M GhoneimDepartment of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia.ORCID 0000-0002-9179-4373
Nour E A Abd El-SattarDepartment of Chemistry, Faculty of Science, Ain Shams University, Abbassia, Cairo 11566, Egypt.ORCID 0000-0001-6680-4448

Funding

Al Jouf University DSR-2021-01-0309
6 · The paper itself

Abstract

Newly designed thiazolidine-2,4-diones

Indexed as

anti-hyperglycemicdockingPPARγsulfonylthioureathiazolidine-2,4-dioneVEGFR-2 inhibitors

Identifiers

PMID35215339
PMCPMC8880361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.