Evidence map›Paper›PMID 35215284›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Gelatin Methacrylate Hydrogel for Tissue Engineering Applications-A Review on Material Modifications.

Sasinan Bupphathong, Carlos Quiroz, Wei Huang, Pei-Feng Chung, Hsuan-Ya Tao, Chih-Hsin Lin

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 143 citations in OpenAlex.

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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sasinan BupphathongGraduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-1897-655X
Carlos QuirozInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-7651-0953
Wei HuangDepartment of Orthodontics, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
Pei-Feng ChungSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-9193-7285
Hsuan-Ya TaoGraduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Chih-Hsin LinGraduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Taipei Medical University · TWRutgers, The State University of New Jersey · US

Funding

Ministry of Science and Technology MOST110-2222-E-038-001-MY3Taipei Medical University TMU108-AE1-B48
6 · The paper itself

Abstract

To recreate or substitute tissue in vivo is a complicated endeavor that requires biomaterials that can mimic the natural tissue environment. Gelatin methacrylate (GelMA) is created through covalent bonding of naturally derived polymer gelatin and methacrylic groups. Due to its biocompatibility, GelMA receives a lot of attention in the tissue engineering research field. Additionally, GelMA has versatile physical properties that allow a broad range of modifications to enhance the interaction between the material and the cells. In this review, we look at recent modifications of GelMA with naturally derived polymers, nanomaterials, and growth factors, focusing on recent developments for vascular tissue engineering and wound healing applications. Compared to polymers and nanoparticles, the modifications that embed growth factors show better mechanical properties and better cell migration, stimulating vascular development and a structure comparable to the natural-extracellular matrix.

Indexed as

biomaterialsGelMAhydrogelmaterial modificationstissue engineeringvascularization

Identifiers

PMID35215284
PMCPMC8878046
OpenAlexW4210695628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.