Evidence map›Paper›PMID 35215232›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

First In Silico Screening of Insect Molecules for Identification of Novel Anti-Parasitic Compounds.

Tom L Gallinger, Samuel Y Aboagye, Wiebke Obermann, Michael Weiss, Arnold Grünweller, Carlo Unverzagt, David L Williams, Martin Schlitzer, Simone Haeberlein

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Computer-Assisted Discovery ofBioinformatics and biology insights · 2024
    Article
  3. Computer-Aided Discovery ofBiomedical engineering and computational biology · 2024
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tom L GallingerDepartment of Pharmaceutical Chemistry, Philipps University Marburg, 35032 Marburg, Germany.ORCID 0000-0003-3001-481X
Samuel Y AboagyeDepartment of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL 60612, USA.ORCID 0000-0001-7702-982X
Wiebke ObermannDepartment of Pharmaceutical Chemistry, Philipps University Marburg, 35032 Marburg, Germany.
Michael WeissBioorganic Chemistry, University of Bayreuth, 95440 Bayreuth, Germany.
Arnold GrünwellerDepartment of Pharmaceutical Chemistry, Philipps University Marburg, 35032 Marburg, Germany.
Carlo UnverzagtBioorganic Chemistry, University of Bayreuth, 95440 Bayreuth, Germany.
David L WilliamsDepartment of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL 60612, USA.
Martin SchlitzerDepartment of Pharmaceutical Chemistry, Philipps University Marburg, 35032 Marburg, Germany.
Simone HaeberleinInstitute of Parasitology, Justus Liebig University Giessen, 35392 Giessen, Germany.
Philipps University of Marburg · DERush University Medical Center · USUniversity of Bayreuth · DEJustus-Liebig-Universität Gießen · DE

Funding

Identification of preclinical drug candidates for the treatment of schistosomiasisR33AI127635 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI PETUKHOV, PAVEL A, THATCHER, GREGORY R. J · 2019 to 2021
$1.3M
Hessian Ministry for Science and the Arts LOEWE Centre DRUIDNational Institute of Allergy and Infectious Diseases AI127635NIAID NIH HHS R33 AI127635
6 · The paper itself

Abstract

Schistosomiasis is a neglected tropical disease caused by blood flukes of the genus

Indexed as

insect compoundsin silico screeningmolecular dockingSchistosoma mansonithioredoxin glutathione reductase

Identifiers

PMID35215232
PMCPMC8877563
OpenAlexW4206841906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.