Evidence map›Paper›PMID 35215216›Full record

ReviewPathogens (Basel, Switzerland)2022

Adaptive Cellular Immunity against African Swine Fever Virus Infections.

Alexander Schäfer, Giulia Franzoni, Christopher L Netherton, Luise Hartmann, Sandra Blome, Ulrike Blohm

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 84 citations in OpenAlex.

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  10. Implications for safety:Frontiers in microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Alexander SchäferFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0002-4258-0651
Giulia FranzoniDepartment of Animal Health, Istituto Zooprofilattico Sperimentale della Sardegna, 07100 Sassari, Italy.ORCID 0000-0003-0987-3863
Christopher L NethertonThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK.ORCID 0000-0002-1286-8590
Luise HartmannFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.
Sandra BlomeFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-5465-5609
Ulrike BlohmFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0003-4597-248X
Friedrich-Loeffler-Institut · DEIstituto Zooprofilattico Sperimentale della Sardegna · ITThe Pirbright Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00001709Biotechnology and Biological Sciences Research Council BBS/E/I/00007031Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Department for Environment Food and Rural Affairs SE1517European Union's Horizon 2020 No 773701UK Research and Innovation BBS/E/I/00007031
6 · The paper itself

Abstract

African swine fever virus (ASFV) remains a threat to global pig populations. Infections with ASFV lead to a hemorrhagic disease with up to 100% lethality in Eurasian domestic and wild pigs. Although myeloid cells are the main target cells for ASFV, T cell responses are impacted by the infection as well. The complex responses remain not well understood, and, consequently, there is no commercially available vaccine. Here, we review the current knowledge about the induction of antiviral T cell responses by cells of the myeloid lineage, as well as T cell responses in infected animals, recent efforts in vaccine research, and T cell epitopes present in ASFV.

Indexed as

adaptive immunityAfrican swine fever virusantigen-presenting cellscytokinesporcine diseaseT cellsvaccines

Identifiers

PMID35215216
PMCPMC8878497
OpenAlexW4212878121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.