Evidence map›Paper›PMID 35215177›Full record

ArticlePathogens (Basel, Switzerland)2022

Enhanced Seroconversion to West Nile Virus Proteins in Mice by West Nile Kunjin Replicon Virus-like Particles Expressing Glycoproteins from Crimean-Congo Hemorrhagic Fever Virus.

Pham-Tue-Hung Tran, Urban Höglund, Olivia Larsson, Sofia Appelberg, Ali Mirazimi, Magnus Johansson, Wessam Melik

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pham-Tue-Hung TranSchool of Medical Science, Inflammatory Response and Infection Susceptibility Centre (iRiSC), Örebro University, 703 62 Örebro, Sweden.ORCID 0000-0002-8366-9310
Urban HöglundAdlego Biomedical AB, P.O. Box 42, 751 03 Uppsala, Sweden.
Olivia LarssonAdlego Biomedical AB, P.O. Box 42, 751 03 Uppsala, Sweden.
Sofia AppelbergDepartment of Microbiology, Public Health Agency of Sweden, 171 82 Solna, Sweden.ORCID 0000-0002-7381-3606
Ali MirazimiDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institution, 141 52 Huddinge, Sweden.
Magnus JohanssonSchool of Medical Science, Inflammatory Response and Infection Susceptibility Centre (iRiSC), Örebro University, 703 62 Örebro, Sweden.
Wessam MelikSchool of Medical Science, Inflammatory Response and Infection Susceptibility Centre (iRiSC), Örebro University, 703 62 Örebro, Sweden.ORCID 0000-0001-9876-6239
Örebro University · SEPublic Health Agency of Sweden · SESwedish Veterinary Agency · SE

Funding

Foundation for Knowledge HÖG19 (20190091)Foundation for Knowledge Synergi 19 (20200063)
6 · The paper itself

Abstract

Removal of genes coding for major parts of capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts the production of infectious virus particles where the remaining genome forms a replicon that retains replicability in host cells. The C-prM-E proteins can also be expressed in

Indexed as

Crimean–Congo hemorrhagic fever virusenvelopeglycoprotein (Gn–Gc)neutralizationnon-structural protein 1repliconsreplicon virus-like particles (RVPs)seroconversionvaccinesWest Nile Kunjin virus

Identifiers

PMID35215177
PMCPMC8874638
OpenAlexW4214697385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.