Evidence map›Paper›PMID 35215139›Full record

ArticlePathogens (Basel, Switzerland)2022

Priority Activities in Child and Adolescent Tuberculosis to Close the Policy-Practice Gap in Low- and Middle-Income Countries.

Karen du Preez, Betina Mendez Alcântara Gabardo, Sushil K Kabra, Rina Triasih, Trisasi Lestari, Margaret Kal, Bazarragchaa Tsogt, Gantsetseg Dorj, Enkhtsetseg Purev, Thu Anh Nguyen and 45 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  11. Drug Resistance and Molecular Characteristics ofJournal of personalized medicine · 2022
    Article
  12. Testing and Scaling Interventions to Improve the Tuberculosis Infection Care Cascade.Journal of the Pediatric Infectious Diseases Society · 2022
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

55 authors.

Karen du PreezDesmond Tutu Tuberculosis Center, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town 8000, South Africa.
Betina Mendez Alcântara GabardoPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Sushil K KabraDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India.ORCID 0000-0003-2616-9157
Rina TriasihFaculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
Trisasi LestariFaculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.ORCID 0000-0002-4799-5338
Margaret KalNational Department of Health, Port Moresby 131, Papua New Guinea.
Bazarragchaa TsogtMongolian Coalition Against Tuberculosis, Ulaanbaatar 210648, Mongolia.
Gantsetseg DorjTuberculosis Surveillance and Research Department, National Center for Communicable Diseases, Ulaanbaatar 210648, Mongolia.
Enkhtsetseg PurevTuberculosis Clinic, National Center for Communicable Diseases, Ulaanbaatar 210648, Mongolia.
Thu Anh NguyenWoolcock Institute of Medical Research, Ha Noi 100000, Vietnam.ORCID 0000-0002-2089-2902
Lenny NaidooHealth Department, Cape Town 8000, South Africa.
Lindiwe MvusiNational TB Control & Management Cluster, National Department of Health, Pretoria 0187, South Africa.
Hendrik Simon SchaafDesmond Tutu Tuberculosis Center, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town 8000, South Africa.
Anneke C HesselingDesmond Tutu Tuberculosis Center, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town 8000, South Africa.
Andrea Maciel de Oliveira RossoniPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Anna Cristina Calçada CarvalhoPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.ORCID 0000-0002-0128-942X
Claudete Aparecida Araújo CardosoPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.ORCID 0000-0002-7638-6814
Clemax Couto Sant'AnnaPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Danielle Gomes Dell' OrtiPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Fernanda Dockhorn CostaPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Liliana Romero VegaPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Maria de Fátima Pombo Sant'AnnaPediatric Tuberculosis Working Group, Ministry of Health, Brasilia 70304-008, Brazil.
Nguyen Binh HoaNational Tuberculosis Program, Ha Noi 100000, Vietnam.
Phan Huu PhucNational Pediatric Hospital, Ha Noi 100000, Vietnam.
Attannon Arnauld FiogbeInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Dissou AffolabiNational Tuberculosis Program, Cotonou 03 BP 2819, Benin.ORCID 0000-0002-5123-3491
Gisèle BadoumInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Abdoul Risgou OuédraogoInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Tandaogo SaouadogoMinistry of Health National Tuberculosis Program, Ouagadougou 03 BP 7047, Burkina Faso.
Adjima CombaryInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Albert Kuate KuateInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Bisso Ngono Annie PrudenceNational Tuberculosis Program, Yaoundé BP 6000, Cameroon.
Aboubakar Sidiki MagassoubaInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Adama Marie BangouraNational Tuberculosis Program, Conakry 63570, Guinea.
Alphazazi SoumanaInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Georges HermanaInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Hervé GandoNational Tuberculosis Program, Bangui BP 729, Central African Republic.
Nafissatou FallInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Barnabé GningNational Tuberculosis Program, Dakar 12000, Senegal.
Mohammed Fall DogoInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Olivia MbitikonInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Manon DeffenseInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Kevin ZimbaLusaka Provincial Health Office, Ministry of Health, Lusaka 10101, Zambia.
Chishala ChabalaDepartment of Pediatrics and Child Health, School of Medicine, University of Zambia, Lusaka 10101, Zambia.
Moorine Penninah SekaddeNational Tuberculosis and Leprosy Program, Kampala 7025, Uganda.
Henry LuzzeNational Tuberculosis and Leprosy Program, Kampala 7025, Uganda.
Stavia TuryahabweNational Tuberculosis and Leprosy Program, Kampala 7025, Uganda.
John Paul DongoThe Union Uganda Office, Kampala 7025, Uganda.
Constantino LopesNational Tuberculosis Program, Ministerio da Saude, Dili NM 87109, Timor-Leste.
Milena Dos SantosHospital Nacional Guido Valadares, Ministerio da Saude, Dili NM 87109, Timor-Leste.
Joshua Reginald FrancisMenzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.ORCID 0000-0001-9302-4543
Magnolia Arango-LoboguerreroColombian Association of Pediatric Pulmonology, National University of Colombia, Bogota 500001, Colombia.
Carlos M Perez-VelezDivision of Infectious Diseases, University of Arizona College of Medicine, Tucson, AZ 85721, USA.
Kobto Ghislain KouraInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.
Stephen M GrahamInternational Union Against Tuberculosis and Lung Disease, 75001 Paris, France.ORCID 0000-0003-3525-2294

Funding

Interdisciplinary and multi-level approach to estimate the disease burden and outcomes of childhood tuberculous meningitis.K43TW011006 · FIC · STELLENBOSCH UNIVERSITY · PI DU PREEZ, KAREN · 2020 to 2024
$622k
FIC NIH HHS K43 TW011006Fogarty International Center of the National Institutes of Health K43TW011006
6 · The paper itself

Abstract

Over the past 15 years, and despite many difficulties, significant progress has been made to advance child and adolescent tuberculosis (TB) care. Despite increasing availability of safe and effective treatment and prevention options, TB remains a global health priority as a major cause of child and adolescent morbidity and mortality-over one and a half million children and adolescents develop TB each year. A history of the global public health perspective on child and adolescent TB is followed by 12 narratives detailing challenges and progress in 19 TB endemic low and middle-income countries. Overarching challenges include: under-detection and under-reporting of child and adolescent TB; poor implementation and reporting of contact investigation and TB preventive treatment services; the need for health systems strengthening to deliver effective, decentralized services; and lack of integration between TB programs and child health services. The COVID-19 pandemic has had a significant negative impact on case detection and treatment outcomes. Child and adolescent TB working groups can address country-specific challenges to close the policy-practice gaps by developing and supporting decentral ized models of care, strengthening clinical and laboratory diagnosis, including of multidrug-resistant TB, providing recommended options for treatment of disease and infection, and forging strong collaborations across relevant health sectors.

Indexed as

adolescentchildnational tuberculosis programtuberculosis

Identifiers

PMID35215139
PMCPMC8878304

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.