Evidence map›Paper›PMID 35215109›Full record

ArticlePathogens (Basel, Switzerland)2022

Antiviral Effects of 5-Aminolevulinic Acid Phosphate against Classical Swine Fever Virus: In Vitro and In Vivo Evaluation.

Shizuka Hirose, Norikazu Isoda, Loc Tan Huynh, Taksoo Kim, Keiichiro Yoshimoto, Tohru Tanaka, Kenjiro Inui, Takahiro Hiono, Yoshihiro Sakoda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Shizuka HiroseLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Hokkaido, Japan.
Norikazu IsodaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Hokkaido, Japan.ORCID 0000-0003-3480-988X
Loc Tan HuynhLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Hokkaido, Japan.ORCID 0000-0001-9922-4802
Taksoo KimLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Hokkaido, Japan.
Keiichiro YoshimotoNeopharma Japan Co., Ltd., Koujimachi 6-2-6, Chiyoda-ku, Tokyo 102-0083, Japan.
Tohru TanakaNeopharma Japan Co., Ltd., Koujimachi 6-2-6, Chiyoda-ku, Tokyo 102-0083, Japan.
Kenjiro InuiNational Center for Veterinary Diagnosis, Tan Chung Chua, Hien Ninh, Soc Son, Hanoi 122000, Vietnam.
Takahiro HionoLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Hokkaido, Japan.
Yoshihiro SakodaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Hokkaido, Japan.ORCID 0000-0001-7021-1688
Hokkaido University · JPOncolys BioPharma (Japan) · JPCan Tho University · VNNational Institute of Veterinary Research · VN

Funding

Ministry of Education, Culture, Sports, Science and Technology JP19H03115Neopharma Japan Co., Ltd. This joint research contract was approved on October 28, 2019.
6 · The paper itself

Abstract

The inhibitory effects of 5-aminolevulinic acid phosphate (5-ALA), an important amino acid for energy production in the host, against viral infections were previously reported. Here, the antiviral effects of 5-ALA against classical swine fever virus (CSFV) belonging to the genus

Indexed as

5-aminolevulinic acid phosphateantiviral effectclassical swine fever virusprotoporphyrin IX

Identifiers

PMID35215109
PMCPMC8877771
OpenAlexW4210742614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.