Evidence map›Paper›PMID 35214943›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Comparable Studies on Nanoscale Antibacterial Polymer Coatings Based on Different Coating Procedures.

Thorsten Laube, Jürgen Weisser, Svea Sachse, Thomas Seemann, Ralf Wyrwa, Matthias Schnabelrauch

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Antibacterial Nanostructured Coatings.Nanomaterials (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Thorsten LaubeINNOVENT e.V., Biomaterials Department, 07745 Jena, Germany.
Jürgen WeisserINNOVENT e.V., Biomaterials Department, 07745 Jena, Germany.ORCID 0000-0001-7721-5155
Svea SachseINNOVENT e.V., Biomaterials Department, 07745 Jena, Germany.
Thomas SeemannINNOVENT e.V., Surface Technology Department, 07745 Jena, Germany.
Ralf WyrwaINNOVENT e.V., Biomaterials Department, 07745 Jena, Germany.ORCID 0000-0003-4556-6510
Matthias SchnabelrauchINNOVENT e.V., Biomaterials Department, 07745 Jena, Germany.ORCID 0000-0002-1968-8058
Innovent · DE

Funding

German Federal Ministry of Economics and Energy MF130124
6 · The paper itself

Abstract

The antibacterial activity of different antibiotic and metal-free thin polymer coatings was investigated. The films comprised quaternary ammonium compounds (QAC) based on a vinyl benzyl chloride (VBC) building block. Two monomeric QAC of different alkyl chain lengths were prepared, and then polymerized by two different polymerization processes to apply them onto Ti surfaces. At first, the polymeric layer was generated directly on the surface by atom transfer radical polymerization (ATRP). For comparison purposes, in a classical route a copolymerization of the QAC-containing monomers with a metal adhesion mediating phosphonate (VBPOH) monomers was carried out and the Ti surfaces were coated via drop coating. The different coatings were characterized by X-ray photoelectron spectroscopy (XPS) illustrating a thickness in the nanomolecular range. The cytocompatibility in vitro was confirmed by both live/dead and WST-1 assay. The antimicrobial activity was evaluated by two different assays (CFU and BTG, resp.,), showing for both coating processes similar results to kill bacteria on contact. These antibacterial coatings present a simple method to protect metallic devices against microbial contamination.

Indexed as

antibacterial activityatom transfer radicalpolymerizationcoatingnanoscalephosphonatequaternary ammonium compounds

Identifiers

PMID35214943
PMCPMC8875251
OpenAlexW4212877267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.