Evidence map›Paper›PMID 35214937›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Strategy for Conjugating Oligopeptides to Mesoporous Silica Nanoparticles Using Diazirine-Based Heterobifunctional Linkers.

Md Arif Khan, Ramy W Ghanim, Maelyn R Kiser, Mahsa Moradipour, Dennis T Rogers, John M Littleton, Luke H Bradley, Bert C Lynn, Stephen E Rankin, Barbara L Knutson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Md Arif KhanDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA.
Ramy W GhanimDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA.
Maelyn R KiserDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA.
Mahsa MoradipourDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA.
Dennis T RogersNaprogenix Inc., UK-ASTeCC, Lexington, KY 40506-0286, USA.
John M LittletonNaprogenix Inc., UK-ASTeCC, Lexington, KY 40506-0286, USA.
Luke H BradleyDepartment of Neuroscience, University of Kentucky, Lexington, KY 40536-0298, USA.
Bert C LynnDepartment of Chemistry, University of Kentucky, Lexington, KY 40506-0055, USA.
Stephen E RankinDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA.
Barbara L KnutsonDepartment of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506-0046, USA.
University of Kentucky · USNaprogenix (United States) · US

Funding

Harvesting specific plant metabolites from hairy root cultures using magnetized nanoparticlesR44AT008312 · NCCIH · NAPROGENIX, INC · PI LITTLETON, JOHN M. · 2017 to 2018
$1.0M
Harvesting specific plant metabolites from hairy root cultures using magnetized nR41AT008312 · NCCIH · NAPROGENIX, INC · PI LITTLETON, JOHN M. · 2014 to 2014
$190k
Kentucky Science and Engineering Foundation KSEF-2929-RDE-016NIH HHS 2R44AT008312-02NIH HHS R41AT008312
6 · The paper itself

Abstract

Successful strategies for the attachment of oligopeptides to mesoporous silica with pores large enough to load biomolecules should utilize the high surface area of pores to provide an accessible, protective environment. A two-step oligopeptide functionalization strategy is examined here using diazirine-based heterobifunctional linkers. Mesoporous silica nanoparticles (MSNPs) with average pore diameter of ~8 nm and surface area of ~730 m

Indexed as

conjugationdiazirineheterobifunctional linkermesoporous silicananoparticleoligopeptide

Identifiers

PMID35214937
PMCPMC8880541
OpenAlexW4213003720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.