Evidence map›Paper›PMID 35214767›Full record

ArticleVaccines2022

An Observational Study to Assess the Effectiveness of 4CMenB against Meningococcal Disease and Carriage and Gonorrhea in Adolescents in the Northern Territory, Australia-Study Protocol.

Helen S Marshall, Prabha H Andraweera, James Ward, John Kaldor, Ross Andrews, Kristine Macartney, Peter Richmond, Vicki Krause, Ann Koehler, David Whiley and 11 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Management and prevention of Neisseria meningitidis and Neisseria gonorrhoeae infections in the context of evolving antimicrobial resistance trends.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  4. 4CMenB journey to the 10-year anniversary and beyond.Human vaccines & immunotherapeutics · 2024
    Review
  5. Zap the clap with DNA: a novel microbicide for preventingAntimicrobial agents and chemotherapy · 2024
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 14 institutions in 3 countries.

Helen S MarshallVaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, Adelaide, SA 5006, Australia.
Prabha H AndraweeraVaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, Adelaide, SA 5006, Australia.ORCID 0000-0003-2434-8370
James WardUQ Poche Centre, The University of Queensland, Saint Lucia, QLD 4072, Australia.
John KaldorThe Kirby Institute, The University of New South Wales, Sydney, NSW 2052, Australia.
Ross AndrewsMenzies School of Health Research, Casuarina, NT 0811, Australia.
Kristine MacartneyDiscipline of Paediatrics and Child Health, The University of Sydney, Sydney, NSW 2006, Australia.
Peter RichmondTelethon Kids Institute and The University of Western Australia, Crawley, WA 6009, Australia.
Vicki KrauseCentre for Disease Control, Department of Health, Northern Territory Government, Darwin, NT 0810, Australia.
Ann KoehlerCommunicable Disease Control Branch, SA Health, South Australian Government, Adelaide, SA 5000, Australia.
David WhileyUQ Centre for Clinical Research, The University of Queensland and Pathology Queensland, Saint Lucia, QLD 4072, Australia.
Lynne GilesSchool of Public Health, The University of Adelaide, Adelaide, SA 5005, Australia.
Rosalind WebbyCentre for Disease Control, Department of Health, Northern Territory Government, Darwin, NT 0810, Australia.
Heather D'AntoineMenzies School of Health Research, Casuarina, NT 0811, Australia.
Jonathan KarnonCollege of Medicine and Public Health, Flinders University, Bedford Park, SA 5001, Australia.
Rob BairdNorthern Territory Pathology, Department of Health, Northern Territory Government, Casuarina, NT 0811, Australia.
Andrew LawrenceSA Pathology, Department of Health, South Australian Government, Adelaide, SA 5000, Australia.
Helen Petousis-HarrisDepartment of General Practice and Primary Health Care, The University of Auckland, Auckland 1023, New Zealand.
Philippe De WalsFaculty of Medicine, The Laval University, Quebec, QC G1V 0A6, Canada.
Belinda Greenwood-SmithCentre for Disease Control, Department of Health, Northern Territory Government, Darwin, NT 0810, Australia.
Michael BinksMenzies School of Health Research, Casuarina, NT 0811, Australia.ORCID 0000-0001-5455-690X
Lisa WhopMenzies School of Health Research, Casuarina, NT 0811, Australia.ORCID 0000-0003-4816-2933
Menzies School of Health Research · AUGovernment of Western Australia Department of Health · AUThe University of Queensland · AUWomen's and Children's Health Network · AUFlinders University · AUGovernment of South Australia · AUGovernment of the Northern Territory · AUSouth Australia Pathology · AUThe Kids Research Institute Australia · AUThe University of Adelaide · AUThe University of Sydney · AUUniversité Laval · CAUniversity of Auckland · NZUNSW Sydney · AU

Funding

National Health and Medical Research Council APP1170965
6 · The paper itself

Abstract

Invasive meningococcal disease (IMD) causes significant morbidity and mortality worldwide with serogroup B being the predominant serogroup in Australia and other countries for the past few decades. The licensed 4CMenB vaccine is effective in preventing meningococcal B disease. Emerging evidence suggests that although 4CMenB impact on carriage is limited, it may be effective against gonorrhoea due to genetic similarities between

Indexed as

4CMenBgonorrhoeameningitismeningococcal diseasevaccinationvaccine

Identifiers

PMID35214767
PMCPMC8880162
OpenAlexW4213187826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.