ReviewVaccines2022
Racial and Ethnic Diversity in SARS-CoV-2 Vaccine Clinical Trials Conducted in the United States.
Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Sex, Racial, and Ethnic Representation in COVID-19 Clinical Trials: A Systematic Review and Meta-analysis.JAMA internal medicine · 2023Pooled it
- Successful recruitment of monolingual Spanish speaking Latinos to university phase II and III outpatient COVID-19 clinical treatment trials in Northern California.Contemporary clinical trials · 2022Trial
- "It's Like Disrupting Internally:" a Qualitative Study of Opportunities and Limitations to Promote Diversity in Participant Recruitment in Health Research.Journal of racial and ethnic health disparities · 2026Article
- Factors that influence clinical trial participation for oncology patients in Australia: a scoping review.BMJ open · 2025Article
- Reducing inequalities through greater diversity in clinical trials - As important for medical devices as for drugs and therapeutics.Contemporary clinical trials communications · 2025Article
- Innovative Development of Research Engagement Manual: Strategies to Enhance Recruitment and Retention of Black Individuals in Clinical Trials for Substance Use Disorders.Health equity · 2025Article
- Levels and functionality of Pacific Islanders' hybrid humoral immune response to BNT162b2 vaccination and delta/omicron infection: A cohort study in New Caledonia.PLoS medicine · 2024Article
- Ethnic Minority Participation in Clinical Trials from Latin America and the Caribbean: A Scoping Review.Journal of immigrant and minority health · 2024Article
- Reassessing human MHC-I genetic diversity in T cell studies.Scientific reports · 2024Article
- Equity Concerns Across Pediatric Research Recruitment: An Analysis of Research Staff Interviews.Academic pediatrics · 2024Article
- Evaluating enrollment and representation in COVID-19 and HIV vaccine clinical trials.Frontiers in public health · 2024Article
- Predictors of willingness to participate in COVID-19 clinical trials among Black and Latino adults.Journal of clinical and translational science · 2024Article
- Factors Associated With Enrollment into Inpatient Coronavirus Disease 2019 Randomized Controlled Trials: A Cross-sectional Analysis.Open forum infectious diseases · 2023Article
- The Impact of Educational Intervention on Willingness to Enroll in a Clinical Trial of a Gonorrhea Vaccine.Vaccines · 2023Article
- Community Health Representatives as Trusted Sources for Increasing Representation of American Indian Communities in Clinical Research.International journal of environmental research and public health · 2023Article
- COVID-19 vaccine attitudes among a majority black sample in the Southern US: public health implications from a qualitative study.BMC public health · 2023Article
- Best Practices in Recruitment and Outreach to Women and Diverse Veterans for Coronavirus Research at the U.S. Department of Veterans Affairs.Health equity · 2023Article
- Lessons from a large-scale COVID-19 vaccine trial.The Journal of clinical investigation · 2022Article
- Article
- Enabling community input to improve equity in and access to translational research: The Community Coalition for Equity in Research.Journal of clinical and translational science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence shows that White and non-Hispanic individuals are overrepresented in clinical trials. The development of new vaccines and drugs, however, necessitates that clinical research trials include representative participants, particularly in light of evidence showing that underrepresented minorities may have a different response to certain medications and vaccines. Racial and ethnic disparities among clinical trials are multilayered and complex, and this requires action. The results of this study indicate that significant racial and ethnic disparities consistently exist among the most recent early SARS-CoV-2 vaccine clinical trials as compared to the pandemic H1N1 vaccine clinical trials of 2009. New strategies, policies, training programs, and reforms are required to address these disparities among clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.