ReviewVaccines2022
Effectiveness and Safety of COVID-19 Vaccine among Pregnant Women in Real-World Studies: A Systematic Review and Meta-Analysis.
Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 7 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Umbrella review of the safety of Chikungunya vaccine platforms used in other vaccines.Human vaccines & immunotherapeutics · 2025Pooled it
- Effectiveness and safety of COVID-19 vaccines on maternal and perinatal outcomes: a systematic review and meta-analysis.BMJ global health · 2024Pooled it
- Neonatal and maternal outcomes of mRNA versus Non-mRNA COVID-19 vaccines in pregnant patients: a systematic review and meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024Pooled it
- Is it safe and effective to administer COVID-19 vaccines during pregnancy? A systematic review and meta-analysis.American journal of infection control · 2023Pooled it
- COVID-19 vaccination during pregnancy: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- COVID-19 vaccine and pregnancy outcomes: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Pooled it
- Association of Infection with Different SARS-CoV-2 Variants during Pregnancy with Maternal and Perinatal Outcomes: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- COVID-19 vaccine uptake and infection among pregnant women in Libya: a cross-sectional study.BMC pregnancy and childbirth · 2025Observational
- Attitudes towards vaccination against COVID-19 during pregnancy and its determinants among people of reproductive age.Human vaccines & immunotherapeutics · 2025Article
- Safety of COVID-19 Vaccines Among Pregnant Women in India: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Factors that influence vaccination communication during pregnancy: provider and patient perspectives using the theoretical domains framework.JBI evidence implementation · 2025Article
- Effect of COVID-19 vaccination on the incidence, lethality and mortality of pregnant and postpartum women.PloS one · 2025Article
- Knowledge and attitudes of pregnant women about COVID-19 vaccination.Revista latino-americana de enfermagem · 2025Article
- Review
- COVID-19 vaccinations pre- and antepartum: a consideration of the evidence and discussion of issues.Archives of gynecology and obstetrics · 2024Review
- Review
- Knowledge, attitude and practice towards COVID-19 among pregnant women in Africa: A systematic review and meta-analysis.Heliyon · 2024Article
- Article
- The effect of coronavirus disease 2019 vaccination on pregnant women: A scoping review.Health SA = SA Gesondheid · 2024Review
- Increasing Vaccine Uptake during Pregnancy by Using Prenatal Education Classes: An Effective Tool for Health Communication and Promotion.Children (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
We aimed to assess the effectiveness and safety of coronavirus disease 2019 (COVID-19) vaccines for pregnant women in real-world studies. We searched for observational studies about the effectiveness and safety of COVID-19 vaccines among vaccinated pregnant women from inception to 6 November 2021. A total of 6 studies were included. We found that vaccination prevented pregnant women from SARS-CoV-2 infection (OR = 0.50, 95% CI, 0.35-0.79) and COVID-19-related hospitalization (OR = 0.50, 95% CI, 0.31-0.82). Messenger-RNA vaccines could reduce the risk of infection in pregnant women (OR = 0.13, 95% CI, 0.03-0.57). No adverse events of COVID-19 vaccination were found on pregnant, fetal, or neonatal outcomes. Our analysis confirmed the effectiveness and safety of COVID-19 vaccines for pregnant women. Policy makers should formulate targeted strategies to improve vaccine coverage in pregnant women.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.