Evidence map›Paper›PMID 35214671›Full record

ReviewVaccines2022

The Ongoing Journey of a

Patricia Martin, Cristina Alaimo

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06615375 (Phase 2b, Double-blind, Placebo-controlled Efficacy Challenge Study With the Shigella Tetravalent Bioconjugate Vaccine Shigella4V2), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06615375 phase2active not recruitingnot on this mapstarted 2024, after this paper: background citation

Phase 2b, Double-blind, Placebo-controlled Efficacy Challenge Study With the Shigella Tetravalent Bioconjugate Vaccine Shigella4V2

TypeinterventionalSponsorLimmaTech Biologics AGRan2024 to 2026Enrolled120ConditionsShigellosisArmsShigella4V2, Placebo
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 39 citations in OpenAlex.

  1. Human vaccines & immunotherapeutics · 2026
    Review
  2. New microbes and new infections · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. A Candidate AcVaccines · 2025
    Article
  15. Article
  16. Article
  17. TestingPharmaceutics · 2024
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Patricia MartinLimmaTech Biologics AG, 8952 Schlieren, Switzerland.
Cristina AlaimoLimmaTech Biologics AG, 8952 Schlieren, Switzerland.
Spital Limmattal · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shigellosis is a serious disease with a major impact, especially in low-income countries where mortality and morbidity are high. In addition, shigellosis among travelers and military personnel is a cause of significant morbidity and contributes to the increase in antimicrobial resistance. The World Health Organization (WHO) considers the development of a

Indexed as

bioconjugateO-antigenShigellavaccines

Identifiers

PMID35214671
PMCPMC8878964
OpenAlexW4210323828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.