Evidence map›Paper›PMID 35214625›Full record

ArticleVaccines2022

COVID-19 Infection in Pregnancy: Obstetrical Risk Factors and Neonatal Outcomes-A Monocentric, Single-Cohort Study.

Antonella Vimercati, Rosalba De Nola, Paolo Trerotoli, Maria Elvira Metta, Gerardo Cazzato, Leonardo Resta, Antonio Malvasi, Archiropita Lepera, Ilaria Ricci, Manuela Capozza and 2 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Do timing and severity of gestational COVID-19 impact perinatal and neonatal outcomes?Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
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  11. Observational
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  15. Intrapartum ultrasound and mother acceptance: A study with informed consent and questionnaire.European journal of obstetrics & gynecology and reproductive biology: X · 2023
    Article
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  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Antonella VimercatiUnit of Obstetrics and Gynecology, Department of Biomedical and Human Oncologic Science, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-9862-1619
Rosalba De NolaUnit of Obstetrics and Gynecology, Department of Biomedical and Human Oncologic Science, University of Bari, 70124 Bari, Italy.ORCID 0000-0002-3486-2237
Paolo TrerotoliMedical Statistics, Department of Biomedical and Human Oncologic Science, University of Bari, 70121 Bari, Italy.ORCID 0000-0001-7102-9108
Maria Elvira MettaMedical Statistics, Department of Biomedical and Human Oncologic Science, University of Bari, 70121 Bari, Italy.
Gerardo CazzatoDepartment of Emergency and Organ Transplant, University of Bari, 70121 Bari, Italy.ORCID 0000-0003-0325-4316
Leonardo RestaDepartment of Emergency and Organ Transplant, University of Bari, 70121 Bari, Italy.ORCID 0000-0003-4335-4776
Antonio MalvasiUnit of Obstetrics and Gynecology, Department of Biomedical and Human Oncologic Science, University of Bari, 70124 Bari, Italy.
Archiropita LeperaUnit of Obstetrics and Gynecology, Department of Biomedical and Human Oncologic Science, University of Bari, 70124 Bari, Italy.
Ilaria RicciUnit of Obstetrics and Gynecology, Department of Biomedical and Human Oncologic Science, University of Bari, 70124 Bari, Italy.
Manuela CapozzaUnit of Neonatology and Intensive Care, Department of Biomedical and Human Oncologic Science, University of Bari, 70100 Bari, Italy.
Nicola LaforgiaUnit of Neonatology and Intensive Care, Department of Biomedical and Human Oncologic Science, University of Bari, 70100 Bari, Italy.ORCID 0000-0002-4610-1216
Ettore CicinelliUnit of Obstetrics and Gynecology, Department of Biomedical and Human Oncologic Science, University of Bari, 70124 Bari, Italy.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 on pregnant women and neonates are mainly unknown, since limited data are available in the literature. We conducted a monocentric and cross-sectional study enrolling 122 un-vaccinated pregnant women with COVID-19 infection tested by RT-PCR nasopharyngeal swab. Only 4.1% of the patients had severe COVID-19 symptoms together with major respiratory symptoms and intensive care unit admission, whereas 35.25% of women had comorbidities and two-thirds of them were overweight or obese. COVID-19 was detected mainly in the third trimester (98.36%) and multiparous women (59.02%). The mode of delivery was influenced by mild-severe COVID-19 symptoms, with a higher number of urgent or emergent cesarean sections than spontaneous or operative vaginal births. Preterm births were associated with high BMI, mode of delivery (higher among cesarean sections), nulliparity, and severe COVID-19 symptoms. In cases of severe COVID-19 symptoms, there was a higher rate of respiratory distress syndrome among newborns. In the end, only the presence of a severe COVID-19 infection worsened the obstetrical and neonatal outcomes, with higher rates of urgent or emergent cesarean section, preterm births, and neonatal respiratory distress syndrome.

Indexed as

COVID-19deliveryneonatal respiratory distress syndrome (RDS)neonatepregnancypreterm birth (PTB)SARS-CoV-2

Identifiers

PMID35214625
PMCPMC8879809
OpenAlexW4207063400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.