Evidence map›Paper›PMID 35214586›Full record

ArticleSensors (Basel, Switzerland)2022

Numerical Study on Death of Squamous Cell Carcinoma Based on Various Shapes of Gold Nanoparticles Using Photothermal Therapy.

Donghyuk Kim, Hyunjung Kim

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donghyuk KimDepartment of Mechanical Engineering, Ajou University, Suwon-si 16499, Gyeonggi-do, Korea.ORCID 0000-0002-1976-1331
Hyunjung KimDepartment of Mechanical Engineering, Ajou University, Suwon-si 16499, Gyeonggi-do, Korea.ORCID 0000-0002-8289-0742
Ajou University · KR

Funding

National Research Foundation of Korea NRF-2018R1A2B2001082
6 · The paper itself

Abstract

Due to increased exposure to ultraviolet radiation caused by increased outdoor activities, the incidence of skin cancer is increasing. Incision is the most typical method for treating skin cancer, and various treatments that can minimize the risks of incision surgery are being investigated. Among them, photothermal therapy is garnering attention because it does not cause bleeding and affords rapid recovery. In photothermal therapy, tumor death is induced via temperature increase. In this study, a numerical study based on heat transfer theory was conducted to investigate the death of squamous cell carcinoma located in the skin layer based on various shapes of gold nanoparticles (AuNPs) used in photothermal therapy. The quantitative correlation between the conditions of various AuNPs and the laser intensity that yields the optimal photothermal treatment effect was derived using the effective apoptosis ratio. It was confirmed that optimal conditions exist for maximizing apoptosis within a tumor tissue and minimizing the thermal damage to surrounding normal tissues when using AuNPs under various conditions. Furthermore, it is envisioned that research result will be utilized as a standard for photothermal treatment in the future.

Indexed as

Carcinoma, Squamous CellMetal NanoparticlesCell Line, TumorGoldHumansPhotothermal TherapyUltraviolet RaysGoldapoptosiscontinuous wave lasergold nanoparticlesheat transferhyperthermianumerical analysisphotothermal therapysquamous cell carcinomathermal damage

Identifiers

PMID35214586
PMCPMC8880560
OpenAlexW4213126826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.