ArticleSensors (Basel, Switzerland)2022
Continuous Lactate Monitoring System Based on Percutaneous Microneedle Array.
Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- A Hitchhiker's Guide to Physical and Cognitive Effort.Sports medicine (Auckland, N.Z.) · 2026Review
- Technologies for equine welfare and performance monitoring under field conditions - Where do we stand?Equine veterinary journal · 2026Review
- Biosensor-Integrated Microneedle Devices for Diagnosis and Treatment of Chronic and Infectious Diseases: Current Status, Trends and Challenges.Biosensors · 2026Review
- Clinical Evaluation of Microneedle Biosensors for Continuous Lactate Monitoring in Critically Ill Patients.ACS sensors · 2026Article
- Wearable Sensors for Health Monitoring.Biosensors · 2026Review
- The application prospect of microneedles for sports injuries: a narrative review.Annals of medicine · 2025Review
- A 3D-Printed PMMA Microneedle-Based TSA-ELISA Platform for Noninvasive Inflammatory Biomarker Detection.Micromachines · 2025Article
- Microneedle-Based Multiplexed Monitoring of Diabetes Biomarkers: Capabilities Beyond Glucose Toward Closed-Loop Theranostic Systems.ACS sensors · 2025Review
- Nanosensors and Microsensors for Body Fluid Monitoring: Various Analyte Detection and Construction Solutions.International journal of molecular sciences · 2025Review
- A Comprehensive Review of Advanced Lactate Biosensor Materials, Methods, and Applications in Modern Healthcare.Sensors (Basel, Switzerland) · 2025Review
- New spin coated multilayer lactate biosensor for acidosis monitoring in continuous flow assisted with an electrochemical pH probe.Mikrochimica acta · 2024Article
- Intradermal Lactate Monitoring Based on a Microneedle Sensor Patch for Enhanced In Vivo Accuracy.ACS sensors · 2024Article
- Kinematic and Physiological Analysis of Medieval Combat Sport Using Motion Analysis, Blood Lactate Measurement, and Heart Rate Monitoring: A Case Study.Sensors (Basel, Switzerland) · 2024Article
- Electrochemical Wearable Biosensors and Bioelectronic Devices Based on Hydrogels: Mechanical Properties and Electrochemical Behavior.Biosensors · 2023Review
- Early Changes in Acute Myocardial Infarction in Pigs: Achieving Early Detection with Wearable Devices.Diagnostics (Basel, Switzerland) · 2023Article
- Need for intensive care admission based on point-of-care measurement of serum lactate levels in early trauma care.Journal of clinical orthopaedics and trauma · 2022Article
- Hollow Microneedles on a Paper Fabricated by Standard Photolithography for the Screening Test of Prediabetes.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactate measurement is important in the fields of sports and medicine. Lactate accumulation can seriously affect an athlete's performance. The most common problem caused by lactate accumulation in athletes is muscle soreness due to excessive exercise. Moreover, from a medical viewpoint, lactate is one of the main prognostic factors of sepsis. Currently, blood sampling is the most common approach to lactate measurement for lactate sensing, and continuous measurement is not available. In this study, a low-cost continuous lactate monitoring system (CLMS) is developed based on a percutaneous microneedle array that uses a three-electrode lactate sensor. The working electrode has an area of 10 mm × 6 mm, including a 3 × 3 array of stainless-steel microneedles. The length, width, and thickness of each needle are 1 mm, 0.44 mm, and 0.03 mm, respectively. The working electrode is then plated with gold, polyaniline, lactate enzyme, Nafion, and Poly(2-hydroxyethyl methacrylate) (poly HEMA). The reference electrode is a 2 × 1 array covered with AgCl, and the counter electrode is a 2 × 1 array plated with gold. The sensor is incorporated into the CLMS and connected to a smartphone application and the cloud. The CLMS was tested on 40 human subjects who rode indoor bicycles, starting at 100 W and increasing in steps of 25 W at intervals of 5 min until exhaustion. The data acquired from the app connected to the CLMS were analyzed to determine the subjects' lactate response to exercise and the feasibility of assessing exercise performance and training exercise intensity by using the proposed system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.