Single-Layer-Graphene-Coated and Gold-Film-Based Surface Plasmon Resonance Prism Coupler Sensor for Immunoglobulin G Detection.

Zhe-Wei Yang, Thi-Thu-Hien Pham, Chin-Chi Hsu, Chi-Hsiang Lien, Quoc-Hung Phan

Abstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Differential Refractometric Biosensor for Reliable Human IgG Detection: Proof of Concept.Biosensors · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhe-Wei YangDepartment of Mechanical Engineering, National United University, Miaoli 36063, Taiwan.

Thi-Thu-Hien PhamDepartment of Biomedical Engineering, International University-Vietnam National University, Ho Chi Minh City 700000, Vietnam.ORCID 0000-0001-5808-3214

Chin-Chi HsuDepartment of Mechanical Engineering, National United University, Miaoli 36063, Taiwan.

Chi-Hsiang LienDepartment of Mechanical Engineering, National United University, Miaoli 36063, Taiwan.

Quoc-Hung PhanDepartment of Mechanical Engineering, National United University, Miaoli 36063, Taiwan.ORCID 0000-0001-5150-1890

Funding

Ministry of Science and Technology of Taiwan 108-2218-E-239-002-MY2National United University 111-NUUPRJ-03Taichung Veterans General Hospital/National United University Joint Research Program 111DCK0100001

6 · The paper itself

Abstract

A graphene-based surface plasmon resonance (SPR) prism coupler sensor is proposed for the rapid detection of immunoglobulin G (IgG) antibodies. The feasibility of the proposed sensor is demonstrated by measuring the IgG concentration in phantom mouse and human serum solutions over the range of 0-250 ng/mL. The results show that the circular dichroism and principal fast axis angle of linear birefringence increase in line with increases in IgG concentration over the considered range. Moreover, the proposed device has a resolution of 5-10 ng/mL and a response time of less than three minutes. In general, the sensor provides a promising approach for IgG detection and has significant potential for rapid infectious viral disease testing applications.

Indexed as

GraphiteSurface Plasmon ResonanceAnimalsBirefringenceGoldImmunoglobulin GMiceGoldGraphiteImmunoglobulin Ggrapheneimmunoglobulin G detectionsurface plasmon resonancevirus infectious disease

Identifiers

PMID35214258

DOI10.3390/s22041362

PMCPMC8962983

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.