Evidence map›Paper›PMID 35214199›Full record

ArticlePharmaceutics2022

An On-Demand Drug Delivery System for Control of Epileptiform Seizures.

Takashi Nakano, Shakila B Rizwan, David M A Myint, Jason Gray, Sean M Mackay, Paul Harris, Christopher G Perk, Brian I Hyland, Ruth Empson, Eng Wui Tan and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Brain-Targeted Drug Delivery.Pharmaceutics · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Takashi NakanoNeurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.ORCID 0000-0003-0707-4486
Shakila B RizwanSchool of Pharmacy, University of Otago, Dunedin 9016, New Zealand.
David M A MyintDepartment of Chemistry, University of Otago, Dunedin 9016, New Zealand.
Jason GrayDepartment of Anatomy, University of Otago, Dunedin 9016, New Zealand.
Sean M MackayDepartment of Chemistry, University of Otago, Dunedin 9016, New Zealand.
Paul HarrisCallaghan Innovation, Wellington 5010, New Zealand.
Christopher G PerkDepartment of Anatomy, University of Otago, Dunedin 9016, New Zealand.
Brian I HylandDepartment of Physiology, University of Otago, Dunedin 9016, New Zealand.
Ruth EmpsonDepartment of Physiology, University of Otago, Dunedin 9016, New Zealand.
Eng Wui TanDepartment of Chemistry, University of Otago, Dunedin 9016, New Zealand.
Keshav M DaniFemtosecond Spectroscopy Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.
John Nj ReynoldsDepartment of Anatomy, University of Otago, Dunedin 9016, New Zealand.
Jeffery R WickensNeurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan.ORCID 0000-0002-8795-1209
University of Otago · NZOkinawa Institute of Science and Technology Graduate University · JPCallaghan Innovation · NZ

Funding

Ministry of Business, Innovation and Employment No. UOOX1403Ministry of Science and Innovation No. UOOX0807Okinawa Institute of Science and Technology, Japan Subsidy funding to JRW, TN, KDOtago Innovation Ltd (NZ). n/aOtago Medical Research Foundation (NZ), n/aRoyal Society of New Zealand Rutherford Discovery Fellowship to JNJR
6 · The paper itself

Abstract

Drug delivery systems have the potential to deliver high concentrations of drug to target areas on demand, while elsewhere and at other times encapsulating the drug, to limit unwanted actions. Here we show proof of concept

Indexed as

laserliposomenanoparticleseizureultrasound

Identifiers

PMID35214199
PMCPMC8879600
OpenAlexW4213367416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.