Evidence map›Paper›PMID 35214189›Full record

ArticlePharmaceutics2022

Stability of Plant Leaf-Derived Extracellular Vesicles According to Preservative and Storage Temperature.

Kimin Kim, Jungjae Park, Yehjoo Sohn, Chan-Eui Oh, Ji-Ho Park, Jong-Min Yuk, Ju-Hun Yeon

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Natural Product-Derived Vesicles in Nanotherapeutics.Journal of extracellular vesicles · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kimin KimDepartment of Integrative Biosciences, University of Brain Education, Cheonan 31228, Korea.ORCID 0000-0002-9595-5496
Jungjae ParkDepartment of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Yehjoo SohnDepartment of Integrative Biosciences, University of Brain Education, Cheonan 31228, Korea.
Chan-Eui OhDepartment of Integrative Biosciences, University of Brain Education, Cheonan 31228, Korea.
Ji-Ho ParkDepartment of Bio and Brain engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0002-0721-0428
Jong-Min YukDepartment of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID 0000-0002-4677-7363
Ju-Hun YeonDepartment of Integrative Biosciences, University of Brain Education, Cheonan 31228, Korea.ORCID 0000-0002-9735-8361

Funding

National Research Foundation of Korea 2021R1A2C2003193
6 · The paper itself

Abstract

Plant-derived extracellular vesicles (EVs) are capable of efficiency delivering mRNAs, miRNAs, bioactive lipids, and proteins to mammalian cells. Plant-derived EVs critically contribute to the ability of plants to defend against pathogen attacks at the plant cell surface. They also represent a novel candidate natural substance that shows potential to be developed for food, cosmetic, and pharmaceutical products. However, although plant-derived EVs are acknowledged as having potential for various industrial applications, little is known about how their stability is affected by storage conditions. In this study, we evaluated the stability of

Indexed as

freeze-thawing cyclesplant-derived extracellular vesiclespreservativestability

Identifiers

PMID35214189
PMCPMC8879201

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.