Evidence map›Paper›PMID 35214144›Full record

ArticlePharmaceutics2022

Silver Nanofunctionalized Stent after Radiofrequency Ablation Suppresses Tissue Hyperplasia and Bacterial Growth.

Yubeen Park, Dong-Sung Won, Ga-Hyun Bae, Dae Sung Ryu, Jeon Min Kang, Ji Won Kim, Song Hee Kim, Chu Hui Zeng, Wooram Park, Sang Soo Lee and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yubeen ParkBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Dong-Sung WonBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Ga-Hyun BaeDepartment of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Bucheon 14662, Korea.
Dae Sung RyuBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Jeon Min KangBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Ji Won KimBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Song Hee KimBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Chu Hui ZengBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.ORCID 0000-0003-3364-4649
Wooram ParkDepartment of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Bucheon 14662, Korea.ORCID 0000-0002-4614-0530
Sang Soo LeeAsan Medical Center, Department of Gastroenterology, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
Jung-Hoon ParkBiomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Science, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.ORCID 0000-0001-9114-7750
Asan Medical Center · KRUlsan College · KRSungkyunkwan University · KR

Funding

Korea Medical Device Development Fund KMDF_PR_20200901_0079National Research Foundation of Korea 2020R1A2C2003604
6 · The paper itself

Abstract

Intraductal radiofrequency (RF) ablation combined with placement of a self-expandable metal stent (SEMS) for malignant biliary obstruction has risks such as stent- and heat-induced biliary sludge and restenosis. Here, we investigated the efficacy of a silver nanoparticles (AgNPs)-coated SEMS to inhibit tissue hyperplasia and bacterial growth caused by RF ablation with stent placement in the rabbit bile duct. The release behavior and antibacterial effects of AgNPs-coated SEMSs were evaluated. Then, SEMSs were successfully placed in all rabbits immediately after RF ablation. Ag ions were rapidly released at the beginning and then showed a gradual release behavior. The AgNPs-coated SEMS significantly inhibited bacterial activity compared to the uncoated SEMS (

Indexed as

antibacterial effectmalignant biliary obstruction (MBO)radiofrequency (RF) ablationself-expandable metal stent (SEMS)silver nanoparticle (AgNP)tissue hyperplasia

Identifiers

PMID35214144
PMCPMC8876892
OpenAlexW4213161262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.