Evidence map›Paper›PMID 35214114›Full record

ReviewPharmaceutics2022

Nanotechnology as a Versatile Tool for

Joice Maria Joseph, Maria Rosa Gigliobianco, Bita Mahdavi Firouzabadi, Roberta Censi, Piera Di Martino

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Fluorinated Human Serum Albumin as PotentialMolecules (Basel, Switzerland) · 2023
    Article
  8. Shortwave Infrared Fluorofluorophores for Multicolor In Vivo Imaging.Angewandte Chemie (International ed. in English) · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joice Maria JosephSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-0929-5867
Maria Rosa GigliobiancoPercuros B.V., 2333 Leiden, The Netherlands.
Bita Mahdavi FirouzabadiSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Roberta CensiSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Piera Di MartinoSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-7657-3556
Università di Camerino · ITPercuros (Netherlands) · NL

Funding

European Commission 777682European Commission 857894European Commission 859908
6 · The paper itself

Abstract

Simultaneously being a non-radiative and non-invasive technique makes magnetic resonance imaging (MRI) one of the highly sought imaging techniques for the early diagnosis and treatment of diseases. Despite more than four decades of research on finding a suitable imaging agent from fluorine for clinical applications, it still lingers as a challenge to get the regulatory approval compared to its hydrogen counterpart. The pertinent hurdle is the simultaneous intrinsic hydrophobicity and lipophobicity of fluorine and its derivatives that make them insoluble in any liquids, strongly limiting their application in areas such as targeted delivery. A blossoming technique to circumvent the unfavorable physicochemical characteristics of perfluorocarbon compounds (PFCs) and guarantee a high local concentration of fluorine in the desired body part is to encapsulate them in nanosystems. In this review, we will be emphasizing different types of nanocarrier systems studied to encapsulate various PFCs and fluorinated compounds, headway to be applied as a contrast agent (CA) in fluorine-19 MRI (

Indexed as

fluorineimaging agentmagnetic resonance imagingnanoparticlesnanosystemsperfluorocarbons

Identifiers

PMID35214114
PMCPMC8874484
OpenAlexW4211134314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.