Evidence map›Paper›PMID 35214112›Full record

ReviewPharmaceutics2022

Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy.

Omnia Ahmed, Nicole Remaliah Samantha Sibuyi, Adewale Oluwaseun Fadaka, Madimabe Abram Madiehe, Ernest Maboza, Mervin Meyer, Greta Geerts

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 69 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Biofabrication of Silver Nanoparticles UsingLife (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Comparative Study ofNanomaterials (Basel, Switzerland) · 2024
    Article
  16. Silver Compounds for Caries Management.International dental journal · 2024
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Omnia AhmedDepartment of Restorative Dentistry, University of the Western Cape, Bellville 7535, South Africa.
Nicole Remaliah Samantha SibuyiDepartment of Science and Innovation (DSI), Mintek Nanotechnology Innovation Centre (NIC) Biolabels Research Node, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0001-7175-5388
Adewale Oluwaseun FadakaDepartment of Science and Innovation (DSI), Mintek Nanotechnology Innovation Centre (NIC) Biolabels Research Node, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.
Madimabe Abram MadieheDepartment of Science and Innovation (DSI), Mintek Nanotechnology Innovation Centre (NIC) Biolabels Research Node, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-3935-467X
Ernest MabozaOral and Dental Research Laboratory, University of the Western Cape, Bellville 7535, South Africa.
Mervin MeyerDepartment of Science and Innovation (DSI), Mintek Nanotechnology Innovation Centre (NIC) Biolabels Research Node, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-8296-4860
Greta GeertsDepartment of Restorative Dentistry, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-6324-4251
Mintek · ZAUniversity of the Western Cape · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral diseases are the most common non-communicable diseases in the world, with dental caries and periodontitis causing major health and social problems. These diseases can progress to systematic diseases and cause disfigurement when left untreated. However, treatment of oral diseases is among the most expensive treatments and often focus on restoration of form and function. Caries prevention has traditionally relied on oral hygiene and diet control, among other preventive measures. In this paper, these measures are not disqualified but are brought into a new context through the use of nanotechnology-based materials to improve these conventional therapeutic and preventive measures. Among inorganic nanomaterials, silver nanoparticles (AgNPs) have shown promising outcomes in dental therapy, due to their unique physicochemical properties and enhanced anti-bacterial activities. As such, AgNPs may provide newer strategies for treatment and prevention of dental infections. However, numerous concerns around the chemical synthesis of nanomaterials, which are not limited to cost and use of toxic reducing agents, have been raised. This has inspired the green synthesis route, which uses natural products as reducing agents. The biogenic AgNPs were reported to be biocompatible and environmentally friendly when compared to the chemically-synthesized AgNPs. As such, plant-synthesized AgNPs can be used as antimicrobial, antifouling, and remineralizing agents for management and treatment of dental infections and diseases.

Indexed as

antimicrobial agentsdental cariesgreen synthesisperiodontitisphytochemicalssilver nanoparticles

Identifiers

PMID35214112
PMCPMC8875651
OpenAlexW4211173785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.