Evidence map›Paper›PMID 35214104›Full record

ArticlePharmaceutics2022

Potent Antiplasmodial Derivatives of Dextromethorphan Reveal the

Antoinette Keita, Jean-François Franetich, Maëlle Carraz, Loïse Valentin, Mallaury Bordessoules, Ludivine Baron, Pierre Bigeard, Florian Dupuy, Valentine Geay, Maurel Tefit and 8 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Antoinette KeitaUMR 261-MERIT, IRD, Université de Paris, 4 Avenue de l'Observatoire, 75006 Paris, France.ORCID 0000-0001-7156-9489
Jean-François FranetichCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
Maëlle CarrazUMR 152 Pharma-Dev, IRD, UPS, Université de Toulouse, 31400 Toulouse, France.ORCID 0000-0001-8538-1567
Loïse ValentinCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.ORCID 0000-0001-9522-272X
Mallaury BordessoulesCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
Ludivine BaronCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
Pierre BigeardCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
Florian DupuyLaboratoire d'Excellence GR-Ex, 75015 Paris, France.
Valentine GeayUMR 8038-CiTCoM, CNRS, Université de Paris, 4 Avenue de l'Observatoire, 75006 Paris, France.
Maurel TefitCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
Véronique SarrasinCNR du Paludisme, AP-HP, Hôpital Bichat-Claude-Bernard, 46 Rue Henri-Huchard, 75018 Paris, France.
Sylvie MichelUMR 8038-CiTCoM, CNRS, Université de Paris, 4 Avenue de l'Observatoire, 75006 Paris, France.ORCID 0000-0002-3993-4041
Catherine LavazecLaboratoire d'Excellence GR-Ex, 75015 Paris, France.
Sandrine HouzéUMR 261-MERIT, IRD, Université de Paris, 4 Avenue de l'Observatoire, 75006 Paris, France.ORCID 0000-0001-9016-3847
Dominique MazierCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
Valérie SoulardCentre d'Immunologie et des Maladies Infectieuses, INSERM, CNRS, Sorbonne Université, 75013 Paris, France.
François-Hugues PoréeISCR UMR CNRS 6226, Faculté de Pharmacie, Université de Rennes 1, 2 Avenue du Pr Léon Bernard, 35000 Rennes, France.ORCID 0000-0003-3344-5260
Romain DuvalUMR 261-MERIT, IRD, Université de Paris, 4 Avenue de l'Observatoire, 75006 Paris, France.
Centre National de la Recherche Scientifique · FRUniversité Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alkaloid tazopsine

Indexed as

blood stagesdextromethorphanhepatic stageshit compoundmalariaN-alkylationPlasmodium bergheiPlasmodium falciparumprophylaxistazopsine

Identifiers

PMID35214104
PMCPMC8876632
OpenAlexW4210904999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.