Evidence map›Paper›PMID 35214054›Full record

ReviewPharmaceutics2022

Synergic Antitumor Effect of Photodynamic Therapy and Chemotherapy Mediated by Nano Drug Delivery Systems.

Mozhgan Aghajanzadeh, Mostafa Zamani, Fereshteh Rajabi Kouchi, Josh Eixenberger, Dorsa Shirini, David Estrada, Farhad Shirini

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 55 citations in OpenAlex.

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  15. MXene (TiMaterials (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mozhgan AghajanzadehDepartment of Chemistry, College of Science, University of Guilan, Rasht 41335-19141, Iran.ORCID 0000-0001-7685-3577
Mostafa ZamaniDepartment of Chemistry, College of Science, University of Guilan, Rasht 41335-19141, Iran.ORCID 0000-0001-7417-0158
Fereshteh Rajabi KouchiMicron School of Materials Science and Engineering, Boise State University, Boise, ID 83725, USA.ORCID 0000-0002-5154-1443
Josh EixenbergerMicron School of Materials Science and Engineering, Boise State University, Boise, ID 83725, USA.
Dorsa ShiriniSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran 1985717443, Iran.
David EstradaMicron School of Materials Science and Engineering, Boise State University, Boise, ID 83725, USA.ORCID 0000-0001-5894-0773
Farhad ShiriniDepartment of Chemistry, College of Science, University of Guilan, Rasht 41335-19141, Iran.ORCID 0000-0002-7204-5000
Micron (United States) · USUniversity of Guilan · IRShahid Beheshti University of Medical Sciences · IR

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Carolyn Hovde Bohach · 2012 to 2026
$59.8M
VPS35 D620N inhibits autophagy through disrupted hyaluronic acid-CD44 signalingP20GM109095 · NIGMS · BOISE STATE UNIVERSITY · PI OXFORD, JULIA THOM · 2014 to 2023
$22.7M
NIGMS NIH HHS P20 GM103408NIGMS NIH HHS P20 GM109095
6 · The paper itself

Abstract

This review provides a summary of recent progress in the development of different nano-platforms for the efficient synergistic effect between photodynamic therapy and chemotherapy. In particular, this review focuses on various methods in which photosensitizers and chemotherapeutic agents are co-delivered to the targeted tumor site. In many cases, the photosensitizers act as drug carriers, but this review, also covers different types of appropriate nanocarriers that aid in the delivery of photosensitizers to the tumor site. These nanocarriers include transition metal, silica and graphene-based materials, liposomes, dendrimers, polymers, metal-organic frameworks, nano emulsions, and biologically derived nanocarriers. Many studies have demonstrated various benefits from using these nanocarriers including enhanced water solubility, stability, longer circulation times, and higher accumulation of therapeutic agents/photosensitizers at tumor sites. This review also describes novel approaches from different research groups that utilize various targeting strategies to increase treatment efficacy through simultaneous photodynamic therapy and chemotherapy.

Indexed as

cancercombination of photodynamic therapy/chemotherapydrug delivery systemsnano photosensitizersnano-platformssynergistic effect

Identifiers

PMID35214054
PMCPMC8880656
OpenAlexW4210800971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.