Evidence map›Paper›PMID 35214049›Full record

ArticlePharmaceutics2022

Increased Activities against Biofilms of the Pathogenic Yeast

Valerie Amann, Ann-Kathrin Kissmann, Markus Krämer, Imke Krebs, Julio A Perez-Erviti, Anselmo J Otero-Gonzalez, Fidel Morales-Vicente, Armando Rodríguez, Ludger Ständker, Tanja Weil and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cm-p5 Peptide Dimers Inhibit Biofilms ofInternational journal of molecular sciences · 2023
    Article
  9. Article
  10. A Polyclonal SELEX Aptamer Library Allows Differentiation ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Valerie AmannInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Ann-Kathrin KissmannInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Markus KrämerInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Imke KrebsInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Julio A Perez-ErvitiCenter for Protein Studies, Faculty of Biology, University of Havana, 25 Str. and I Str., La Habana 10400, Cuba.
Anselmo J Otero-GonzalezCenter for Protein Studies, Faculty of Biology, University of Havana, 25 Str. and I Str., La Habana 10400, Cuba.ORCID 0000-0002-1719-0117
Fidel Morales-VicenteGeneral Chemistry Department, Faculty of Chemistry, University of Havana, Zapata y G, La Habana 10400, Cuba.
Armando RodríguezCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Ludger StändkerCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Tanja WeilMax Planck Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419
Universität Ulm · DEUniversity of Havana · CUMax Planck Institute for Polymer Research · DE

Funding

Alexander von Humboldt Foundation 1160914Baden-Württemberg Stiftung BiofMO_005Deutsche Forschungsgemeinschaft CRC1279Federal Ministry of Education and Research BMBF/DLR 01DN18009German Academic Exchange Service 57592717Horizon 2020 686271Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg 7533-10-5-186A and 7533-10-5-190
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are an alternative group for the therapy of infectious diseases, with activity against a wide range of diverse pathogens. However, classical AMPs have significant side effects in human cells due to their unspecific pore formation in biomembranes. Nevertheless, AMPs are promising therapeutics and can be isolated from natural sources, which include sea and freshwater molluscs. The AMPs identified in these organisms show promising antimicrobial activities, as pathogens are mainly fought by innate defence mechanisms. An auspicious candidate among molluscs is the Cuban freshwater snail

Indexed as

antibiofilm activityantimicrobial peptidesCandida albicans

Identifiers

PMID35214049
PMCPMC8877593
OpenAlexW4210799753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.