Evidence map›Paper›PMID 35214027›Full record

ReviewPharmaceutics2022

Colchicine in Managing Skin Conditions: A Systematic Review.

Stefano Dastoli, Steven Paul Nisticò, Pietro Morrone, Cataldo Patruno, Antonio Leo, Rita Citraro, Luca Gallelli, Emilio Russo, Giovambattista De Sarro, Luigi Bennardo

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Guideline
  2. Review
  3. Review
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Use of Biological Drugs for Psoriasis: A Drug-Utilization Study Using Tuscan Administrative Databanks.International journal of environmental research and public health · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Effects of Green Tea (Healthcare (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Stefano DastoliDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Steven Paul NisticòDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Pietro MorroneAzienda Ospedaliera di Cosenza, 87100 Cosenza, Italy.
Cataldo PatrunoDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0001-8661-2822
Antonio LeoDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Rita CitraroDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0001-6746-6751
Luca GallelliDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0003-0858-7902
Emilio RussoDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-1279-8123
Giovambattista De SarroDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Luigi BennardoDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-0434-1027
Magna Graecia University · ITAzienda Ospedaliera di Cosenza · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Colchicine is a natural alkaloid with anti-inflammatory properties used to treat various disorders, including some skin diseases. This paper aims to incorporate all the available studies proposing colchicine as a treatment alternative in the management of cutaneous conditions. (2) Methods: In this systematic review, the available articles present in various databases (PubMed, Scopus-Embase, and Web of Science), proposing colchicine as a treatment for cutaneous pathological conditions, have been selected. Exclusion criteria included a non-English language and non-human studies. (3) Results: Ninety-six studies were included. Most of them were case reports and case series studies describing colchicine as single therapy, or in combination with other drugs. Hidradenitis suppurativa, pyoderma gangrenosum, erythema nodosum, erythema induratum, storage diseases, perforating dermatosis, bullous diseases, psoriasis, vasculitis, acne, urticaria, stomatitis, actinic keratosis, and pustular dermatosis were the main diseases discussed in literature. Although the therapeutic outcomes were variable, most of the studies reported, on average, good clinical results (4) Conclusions: Colchicine could be, as a single therapy or in combination with other drugs, a possible treatment to manage several skin diseases.

Indexed as

colchicinedermatologypustular dermatoses

Identifiers

PMID35214027
PMCPMC8878049
OpenAlexW4210475059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.