Evidence map›Paper›PMID 35214026›Full record

ArticlePharmaceutics2022

Monoketonic Curcuminoid-Lidocaine Co-Deliver Using Thermosensitive Organogels: From Drug Synthesis to Epidermis Structural Studies.

Aryane A Vigato, Ian P Machado, Matheus Del Valle, Patricia A da Ana, Anderson F Sepulveda, Fabiano Yokaichiya, Margareth K K D Franco, Messias C Loiola, Giovana R Tófoli, Cintia Maria S Cereda and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Aryane A VigatoHuman and Natural Sciences Center, Federal University of ABC, Sao Paulo 09210-580, SP, Brazil.
Ian P MachadoDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Sao Paulo 05508-000, SP, Brazil.ORCID 0000-0002-7467-2606
Matheus Del ValleCenter of Engineering, Modeling and Applied Social Sciences, Federal University of ABC, Sao Bernardo 09606-045, SP, Brazil.
Patricia A da AnaCenter of Engineering, Modeling and Applied Social Sciences, Federal University of ABC, Sao Bernardo 09606-045, SP, Brazil.
Anderson F SepulvedaHuman and Natural Sciences Center, Federal University of ABC, Sao Paulo 09210-580, SP, Brazil.ORCID 0000-0003-0441-8618
Fabiano YokaichiyaDepartment Quantum Phenomena in Novel Materials, Helmholtz-Zentrum Berlin für Materialien, 14109 Berlin, Germany.
Margareth K K D FrancoNuclear and Energy Research Institute, Sao Paulo 01000-000, SP, Brazil.
Messias C LoiolaHuman and Natural Sciences Center, Federal University of ABC, Sao Paulo 09210-580, SP, Brazil.
Giovana R TófoliSão Leopoldo Mandic Research Unit, Campinas 13000-000, SP, Brazil.
Cintia Maria S CeredaSão Leopoldo Mandic Research Unit, Campinas 13000-000, SP, Brazil.
Mirela I de SairreHuman and Natural Sciences Center, Federal University of ABC, Sao Paulo 09210-580, SP, Brazil.ORCID 0000-0002-6931-4214
Daniele R de AraujoHuman and Natural Sciences Center, Federal University of ABC, Sao Paulo 09210-580, SP, Brazil.ORCID 0000-0002-9289-4229
Universidade Federal do ABC · BRFaculdade São Leopoldo Mandic · BRHelmholtz-Zentrum Berlin für Materialien und Energie · DEUniversidade de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001National Council for Scientific and Technological Development 307718/2019-0São Paulo Research Foundation 2019/14773-8São Paulo Research Foundation 2019/20303-4
6 · The paper itself

Abstract

Organogels (ORGs) are remarkable matrices due to their versatile chemical composition and straightforward preparation. This study proposes the development of ORGs as dual drug-carrier systems, considering the application of synthetic monoketonic curcuminoid (m-CUR) and lidocaine (LDC) to treat topical inflammatory lesions. The monoketone curcuminoid (m-CUR) was synthesized by using an innovative method via a NbCl

Indexed as

curcuminoidslidocaineorganogelspoloxamerskin structural analysis

Identifiers

PMID35214026
PMCPMC8879257
OpenAlexW4210537583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.