Evidence map›Paper›PMID 35213975›Full record

ArticlePharmaceutics2022

María Gaibar, Apolonia Novillo, Alicia Romero-Lorca, Diego Malón, Beatriz Antón, Amalia Moreno, Ana Fernández-Santander

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Cancers · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

María GaibarHealth Sciences Faculty, Universidad Francisco de Vitoria, 28223 Madrid, Spain.ORCID 0000-0003-3881-8345
Apolonia NovilloBiomedical and Health Sciences Faculty, Universidad Europea de Madrid, 28670 Madrid, Spain.ORCID 0000-0003-0902-0991
Alicia Romero-LorcaBiomedical and Health Sciences Faculty, Universidad Europea de Madrid, 28670 Madrid, Spain.
Diego MalónDepartment of Oncology, University Hospital of Fuenlabrada, 28942 Madrid, Spain.
Beatriz AntónDepartment of Oncology, University Hospital of Fuenlabrada, 28942 Madrid, Spain.
Amalia MorenoDepartment of Oncology, University Hospital of Fuenlabrada, 28942 Madrid, Spain.
Ana Fernández-SantanderBiomedical and Health Sciences Faculty, Universidad Europea de Madrid, 28670 Madrid, Spain.ORCID 0000-0001-7545-1170
Hospital Universitario de Fuenlabrada · ESUniversidad Europea de Madrid · ESUniversidad Francisco de Vitoria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HER2-positive breast cancer (BC) is an aggressive subtype that affects 20-25% of BC patients. For these patients, neoadjuvant therapy is a good option that targets a pathological complete response (pCR) and more breast-conserving surgery. In effect, the outcomes of patients with HER2-positive BC have dramatically improved since the introduction of anti-HER2 antibodies such as trastuzumab (TZ) and/or pertuzumab (PZ) added to chemotherapy. This study sought to examine whether correlation exists between copy number variations (CNVs) in several genes related to the PI3K/AKT pathway (

Indexed as

anti-HER2 treatmentCNVsFGFR1 geneHER2-positive breast cancerMiller–Payne gradingpathological complete response

Identifiers

PMID35213975
PMCPMC8875219
OpenAlexW4206030318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.