Observational studyEndoscopy2022
Efficacy of endoscopic ligation with O-ring closure for prevention of bleeding after gastric endoscopic submucosal dissection under antithrombotic therapy: a prospective observational study.
Observational study in Endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 21 citations in OpenAlex.
- The Hedgehog Method Following Gastric Endoscopic Submucosal Dissection: Observed Postoperative Bleeding Rates Across BEST-J Risk Categories.Digestive diseases and sciences · 2026Article
- Feasibility of Zeosuture M for gastric endoscopic submucosal dissection defect closure during anticoagulation: a preclinical porcine study from Japan.Clinical endoscopy · 2026Article
- Review
- Feasibility of Endoscopic Closure Method Using Low Cost Clips With Thread for Post Gastric Endoscopic Submucosal Dissection: A Pilot Study.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Sprayable gelatin microparticles prevent delayed gastric bleeding in an anticoagulated swine model.Scientific reports · 2026Article
- A novel enhanced two-tooth clip for reliable defect closure endoscopically: An ex vivo comparative and in vivo feasibility study.Surgical endoscopy · 2026Article
- Band-ligation followed by anchor pronged clips for greater post-endoscopic submucosal dissection defect closure.Endoscopy · 2025Article
- Article
- The competency of the novel through-the-scope suture device for gastric mucosal defects: In vivo study in a porcine model (with video).DEN open · 2025Article
- Endoscopic closure using a dedicated device following gastric endoscopic submucosal dissection: Multicenter, prospective, observational pilot study.Endoscopy international open · 2025Article
- Efficacy of alternate mucosa-submucosa clip closure in preventing postoperative adverse events for patients with gastric mucosal lesions after endoscopic submucosal dissection: a multicenter retrospective study.Therapeutic advances in gastroenterology · 2025Article
- Article
- Closure methods for large defects after gastrointestinal endoscopic submucosal dissection.Journal of gastroenterology and hepatology · 2024Review
- Systematic review of self-assembling peptides as topical agents for treatment and prevention of gastrointestinal bleeding.Clinical endoscopy · 2024Article
- Article
- Novel strategy of hold-and-drag clip closure with mantis-like claw for post-gastric endoscopic submucosal dissection defect of <30 mm.Endoscopy · 2023Article
- Effective and Secure Closure after Duodenal Endoscopic Submucosal Dissection: Combination of Endoscopic Ligation with O-Ring Closure and Over-the-Scope Clip.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe examined the efficacy of a novel endoscopic ligation technique with O-ring closure (E-LOC) to prevent bleeding after gastric endoscopic submucosal dissection (ESD) under antithrombotic therapy.
methodsThis single-center prospective study involved consecutive patients who were taking antithrombotic agents and underwent gastric ESD. E-LOC was performed by anchoring the nylon loop with hemoclips on both defect edges and/or the exposed muscle layer, and using O-ring band ligation around these deployed clips. The primary outcome was post-ESD bleeding rate. Secondary outcomes were complete closure rate, procedure time, sustained closure rate, and complications.
results48 patients were finally analyzed. The post-ESD bleeding rate was 0 %, the complete closure rate was 97.9 %, and the mean closure time was 29.9 minutes. The sustained closure rate was 95.8 % at postoperative day 2-3 and 33.3 % at postoperative day 10-11. No complications occurred.
conclusionE-LOC may be an effective option for closing mucosal defects after gastric ESD under antithrombotic therapy. However, the preventive effect on post-ESD bleeding should be further investigated in high risk groups.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.