ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2022
The complex relationship between depression and progression to incident cognitive impairment across race and ethnicity.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- A systematic review/meta-analysis of prevalence and incidence rates illustrates systemic underrepresentation of individuals racialized as Asian and/or Asian-American in ADRD research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Prevalence, risk factors, and racial disparities in probable and possible dementia: the national health and aging trends study.The journal of prevention of Alzheimer's disease · 2026Article
- Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Risk factors and population attributable fraction for dementia in American Indians: The Strong Heart Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Clinical Associations and Possible Risk Factors for Affective Neuropsychiatric Symptoms in Older Adults With and Without Cognitive Impairment.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- Invited commentary: improving spatial exposure data for everyone-life-course social context and ascertaining residential history.American journal of epidemiology · 2025Article
- A model to address healthcare gaps and poor research participation in Hispanic patients with Parkinson's disease.Frontiers in aging neuroscience · 2025Article
- Differential associations of neighborhood disadvantage, race/ethnicity, and cognitive status with experiences of psychosocial distress in the HABS-HD cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Major Depressive Disorder and Driving Behavior Among Older Adults.JAMA network open · 2024Article
- Ethno-racial differences in depressive symptom endorsement: Evaluation of brief forms of the Geriatric Depression Scale in older adults.Journal of affective disorders · 2024Article
- Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities.Brain imaging and behavior · 2024Article
- Traumatic Brain Injury, Seizures, and Cognitive Impairment Among Older Adults.JAMA network open · 2024Article
- Association of cognitive impairment with the interaction between chronic kidney disease and depression: findings from NHANES 2011-2014.BMC psychiatry · 2024Article
- Depression, Vascular Burden, and Dementia Prevalence in Late Middle-Aged and Older Black Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Correlation between hearing loss and mild cognitive impairment in the elderly population: Mendelian randomization and cross-sectional study.Frontiers in aging neuroscience · 2024Article
- Is Multidimensional Poverty Associated to Dementia Risk? The Case of Older Adults in Pakistan.Innovation in aging · 2024Article
- Neuropsychiatric Symptoms and Alzheimer Disease Biomarkers Independently Predict Progression to Incident Cognitive Impairment.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Article
- Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities.Research square · 2023Article
- Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Review
- Racial and ethnic differences in neuropsychiatric symptoms and progression to incident cognitive impairment among community-dwelling participants.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
introductionWe examined baseline differences in depression and antidepressant use among cognitively normal older adults in five ethnoracial groups and assessed whether depression predicted a faster progression to incident cognitive impairment across groups.
methodsData from the National Alzheimer's Coordinating Center (n = 8168) were used to examine differences between non-Hispanic Whites (nHW), African Americans (AA), Hispanics, Asians, and American Indian and Alaskan Natives in cross-sectional and longitudinal models.
resultsAA had a lower risk of depression compared to nHW at baseline. No statistical interactions were noted between ethnoracial groups and depression. However, depression independently predicted a faster progression to incident cognitive impairment. Hispanics and Asian participants had a higher hazard for progression compared to nHW. DISCUSSION: Previously established risk factors between depression and dementia were not found among AA and nHW participants. The relationship between depression and ethnoracial groups is complex and suggests differential effects on progression from cognitive normality to impairment.
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