Evidence map›Paper›PMID 35213668›Full record

Trial reportPloS one2022

Progress towards controlling the HIV epidemic in urban Ethiopia: Findings from the 2017-2018 Ethiopia population-based HIV impact assessment survey.

Sileshi Lulseged, Zenebe Melaku, Abebe Habteselassie, Christine A West, Terefe Gelibo, Wudinesh Belete, Fana Tefera, Mansoor Farahani, Minilik Demissie, Wondimu Teferi and 4 more

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  6. Incidence and Predictors of Severe Adverse Drug Reactions among Patients on Antiretroviral Drugs in Harari Regional State, Eastern Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Sileshi LulsegedICAP in Ethiopia, Mailman School of Public Health, Columbia University, Addis Ababa, Ethiopia.ORCID 0000-0001-6801-7034
Zenebe MelakuICAP in Ethiopia, Mailman School of Public Health, Columbia University, Addis Ababa, Ethiopia.
Abebe HabteselassieDepartment of HIV and TB, Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
Christine A WestDivision of Global HIV and TB, Centre for Global Health, Centres for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Terefe GeliboICAP in Ethiopia, Mailman School of Public Health, Columbia University, Addis Ababa, Ethiopia.
Wudinesh BeleteDepartment of HIV and TB, Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
Fana TeferaCare and Treatment Branch, United States Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.
Mansoor FarahaniICAP, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
Minilik DemissieDepartment of HIV and TB, Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
Wondimu TeferiCare and Treatment Branch, United States Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.
Saro AbdellaDepartment of HIV and TB, Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
Sehin BirhanuDivision of Global HIV and TB, Centre for Global Health, Centres for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Christine E RossCare and Treatment Branch, United States Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.
EPHIA Study Group
Ethiopian Public Health Institute · ETAfrica Centres for Disease Control and Prevention · ETCenter for Global Health · USColumbia University · US

Funding

CGH CDC HHS U2G GH001226
6 · The paper itself

Abstract

introductionIn 2014, the Joint United Nations Programme on HIV/AIDS set an 'ambitious' 90-90-90 target for 2020. By 2016, there were disparities observed among countries in their progress towards the targets and some believed the targets were not achievable. In this report, we present the results of data from the Ethiopia Population-based HIV Impact Assessment survey analyzed to assess progress with the targets and associated factors.

methodsWe conducted a nationally representative survey in urban areas of Ethiopia. Socio-demographic and behavioural data were collected from consenting participants using a structured interview. HIV testing was done following the national HIV rapid testing algorithm and seropositivity confirmed using a supplemental laboratory assay. HIV viral suppression was considered if the viral load was <1,000 RNA copies/ml. Screening antiretroviral drugs was done for efavirenz, lopinavir, and tenofovir, which were in use during the survey period. In this analysis, we generated weighted descriptive statistics and used bivariate and logistic regression analysis to examine for associations. The 95% confidence interval was used to measure the precision of estimates and the significance level set at p<0.05.

resultsOf 19,136 eligible participants aged 15-64 years, 614 (3% [95% CI: 0.8-3.3]) were HIV-positive, of which 79.0% (95% CI: 4.7-82.7) were aware of their HIV status, and 97.1% (95% CI: 95.0-98.3 were on antiretroviral therapy, of which 87.6% (95% CI: 83.9-90.5) achieved viral load suppression. Awareness about HIV-positive status was significantly higher among females (aOR = 2.8 [95% CI: 1.38-5.51]), significantly increased with age, the odds being highest for those aged 55-64 years (aOR = 11.4 [95% CI: 2.52-51.79]) compared to those 15-24 years, and was significantly higher among those who used condom at last sex in the past 12 months (aOR = 5.1 [95% CI: 1.68-15.25]). Individuals with secondary education and above were more likely to have achieved viral suppression (aOR = 8.2 [95% CI: 1.82-37.07]) compared with those with no education.

conclusionEthiopia made encouraging progress towards the UNAIDS 90-90-90 targets. The country needs to intensify its efforts to achieve the targets. A particular focus is required to fill the gaps in knowledge of HIV-positive status to increase case identification among population groups such as males, the youth, and those with low education.

Indexed as

Acquired Immunodeficiency SyndromeHIV-1Urban PopulationAdolescentAdultAnti-Retroviral AgentsEpidemicsEthiopiaFemaleHumansMaleMiddle AgedPrevalenceAnti-Retroviral Agents

Identifiers

PMID35213668
PMCPMC8880883
OpenAlexW4214513311

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.