Evidence map›Paper›PMID 35213646›Full record

ArticlePloS one2022

A novel emergency medical services protocol to improve treatment time for large vessel occlusion strokes.

Nancy Glober, Michael Supples, Sarah Persaud, David Kim, Mark Liao, Michele Glidden, Dan O'Donnell, Christopher Tainter, Malaz Boustani, Andreia Alexander

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nancy GloberDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.ORCID 0000-0001-5769-3651
Michael SupplesDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.ORCID 0000-0001-5999-4554
Sarah PersaudDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
David KimDepartment of Emergency Medicine, Stanford University, Santa Clara County, California, United States of America.
Mark LiaoDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Michele GliddenDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Dan O'DonnellDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Christopher TainterDepartment of Anesthesiology Critical Care, University of California at San Diego, San Diego, California, United States of America.
Malaz BoustaniDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Andreia AlexanderDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Indiana University School of MedicineStanford University · US

Funding

Leveraging Infrastructure to train investigators in patient centered outcomes research in the learning health system (LITI-PCORLHS)K12HS026390 · AHRQ · INDIANA UNIVERSITY INDIANAPOLIS · PI CARROLL, AARON E., EMBI, PETER J. · 2018 to 2022
$3.4M
AHRQ HHS K12 HS026390
6 · The paper itself

Abstract

In many systems, patients with large vessel occlusion (LVO) strokes experience delays in transport to thrombectomy-capable centers. This pilot study examined use of a novel emergency medical services (EMS) protocol to expedite transfer of patients with LVOs to a comprehensive stroke center (CSC). From October 1, 2020 to February 22, 2021, Indianapolis EMS piloted a protocol, in which paramedics, after transporting a patient with a possible stroke remained at the patient's bedside until released by the emergency department or neurology physician. In patients with possible LVO, EMS providers remained at the bedside until the clinical assessment and CT angiography (CTA) were complete. If indicated, the paramedics at bedside transferred the patient, via the same ambulance, to a nearby thrombectomy-capable CSC with which an automatic transfer agreement had been arranged. This five-month mixed methods study included case-control assessment of use of the protocol, number of transfers, safety during transport, and time saved in transfer compared to emergent transfers via conventional interfacility transfer agencies. In qualitative analysis EMS providers, and ED physicians and neurologists at both sending and receiving institutions, completed e-mail surveys on the process, and offered suggestions for process improvement. Responses were coded with an inductive content analysis approach. The protocol was used 42 times during the study period; four patients were found to have LVOs and were transferred to the CSC. There were no adverse events. Median time from decision-to-transfer to arrival at the CSC was 27.5 minutes (IQR 24.5-29.0), compared to 314.5 minutes (IQR 204.0-459.3) for acute non-stroke transfers during the same period. Major themes of provider impressions included: incomplete awareness of the protocol, smooth process, challenges when a stroke alert was activated after EMS left the hospital, greater involvement of EMS in patient care, and comments on communication and efficiency. This pilot study demonstrated the feasibility, safety, and efficiency of a novel approach to expedite endovascular therapy for patients with LVOs.

Indexed as

Clinical ProtocolsEmergency Medical ServicesTime-to-TreatmentAgedArterial Occlusive DiseasesComputed Tomography AngiographyFemaleHumansIschemic StrokeMaleMiddle AgedNeurologistsPatient TransferPhysiciansPilot ProjectsStroke

Identifiers

PMID35213646
PMCPMC8880856
OpenAlexW4214729796

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.