ArticleInvestigative ophthalmology & visual science2022
Effect of Viewing Conditions on Fixation Eye Movements and Eye Alignment in Amblyopia.
Article in Investigative ophthalmology & visual science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 27 citations in OpenAlex.
- Abnormal Fixational Eye Movements in Ophthalmic Disease: Implications for Visual Function and Clinical Assessment.Journal of eye movement research · 2026Review
- Machine Learning-Based Prediction of Strabismus with and without Amblyopia from Fixation Eye Movements.Ophthalmology science · 2026Article
- Visually Guided Saccades in Amblyopia and Strabismus: The Roles of Sensory Deficits and Nystagmus.Investigative ophthalmology & visual science · 2026Article
- Differential Fixation and Eye Alignment Patterns in Strabismus with and Without Amblyopia Across Viewing Conditions.Journal of eye movement research · 2026Article
- Application of Eye-Tracking Technology in Assessing Binocular Vision Function in Paediatric Populations: A Scoping Review.Journal of eye movement research · 2026Review
- "Look Versus See": Does Varying Fellow Eye Contrast Affect Perception of the Amblyopic Eye?Investigative ophthalmology & visual science · 2026Article
- Evaluating lawful relationships in saccadic eye movements with simulated vision impairment: A proof-of-concept study.Journal of vision · 2026Article
- Exploration of visual perception metrics as indicators for myopia screening.Lasers in medical science · 2025Article
- Determining fixation accuracy with optical coherence tomography and its implication on visual acuity in amblyopia.Vision research · 2025Article
- Eye tracking for the classification of visual function in individuals with vision impairment: A validation in Para athletes.Journal of vision · 2025Article
- An Eye Movement Monitoring Tool: Towards a Non-Invasive Device for Amblyopia Treatment.Sensors (Basel, Switzerland) · 2025Article
- Dichoptic Visual Search at Varied Fellow Eye Contrasts and Visual Function Deficits in Amblyopia.Investigative ophthalmology & visual science · 2025Article
- Binocular and Fellow Eye Acuity Deficits in Amblyopia: Impact of Fixation Instability and Sensory Factors.Journal of eye movement research · 2025Article
- The impact of eye movements on amblyopic vision: A mini-review.Vision research · 2025Review
- Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia.Investigative ophthalmology & visual science · 2024Article
- Assessing inter-ocular fixational eye movements throughout the lifespan.Experimental brain research · 2024Article
- Multifaceted Interactions of Stereoacuity, Inter-Ocular Suppression, and Fixation Eye Movement Abnormalities in Amblyopia and Strabismus.Investigative ophthalmology & visual science · 2024Article
- Current Developments in the Management of Amblyopia with the Use of Perceptual Learning Techniques.Medicina (Kaunas, Lithuania) · 2023Review
- Cortical Reorganization After Optical Alignment in Strabismic Patients Outside of Critical Period.Investigative ophthalmology & visual science · 2023Article
- Ocular and visual perceptive factors associated with treatment outcomes in patients with anisometropic amblyopia.BMC ophthalmology · 2023Observational
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
Purpose: Patients with amblyopia are known to have fixation instability, which arises from alteration of physiologic fixation eye movements (FEMs) and nystagmus. We assessed the effects of monocular, binocular, and dichoptic viewing on FEMs and eye alignment in patients with and without fusion maldevelopment nystagmus (FMN). Methods: Thirty-four patients with amblyopia and seven healthy controls were recruited for this study. Eye movements were recorded using infrared video-oculography during (1) fellow eye viewing (FEV), (2) amblyopic eye viewing (AEV), (3) both eye viewing (BEV), and (4) dichoptic viewing (DcV) at varying fellow eye (FE) contrasts. The patients were classified per the clinical type of amblyopia and FEM waveforms into those without nystagmus, those with nystagmus with and without FMN. Fixational saccades and intersaccadic drifts, quick and slow phases of nystagmus, and bivariate contour ellipse area were analyzed in the FE and amblyopic eye (AE). Results: We found that FEMs are differentially affected with increased amplitude of quick phases of FMN observed during AEV than BEV and during DcV at lower FE contrasts. Increased fixation instability was seen in anisometropic patients at lower FE contrasts. Incomitance of eye misalignment was seen with the greatest increase during FEV. Strabismic/mixed amblyopia patients without FMN were more likely to demonstrate a fixation switch where the AE attends to the target during DcV than patients with FMN. Conclusions: Our findings suggest that FEM abnormalities modulate with different viewing conditions as used in various amblyopia therapies. Increased FEM abnormalities could affect the visual function deficits and may have treatment implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.