Evidence map›Paper›PMID 35212716›Full record

ArticleTranslational vision science & technology2022

Application of Artificial Intelligence and Deep Learning for Choroid Segmentation in Myopia.

Hung-Ju Chen, Yu-Len Huang, Siu-Lun Tse, Wei-Ping Hsia, Chung-Hao Hsiao, Yang Wang, Chia-Jen Chang

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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  14. IMI 2023 Digest.Investigative ophthalmology & visual science · 2023
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  16. Artificial intelligence technology for myopia challenges: A review.Frontiers in cell and developmental biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hung-Ju ChenDepartment of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.
Yu-Len HuangDepartment of Computer science, Tunghai University, Taichung, Taiwan.
Siu-Lun TseDepartment of Computer science, Tunghai University, Taichung, Taiwan.
Wei-Ping HsiaDepartment of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.
Chung-Hao HsiaoDepartment of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.
Yang WangDepartment of Computer science, Tunghai University, Taichung, Taiwan.
Chia-Jen ChangDepartment of Optometry, Central Taiwan University of Science and Technology, Taichung City, Taiwan.
Taichung Veterans General Hospital · TWTunghai University · TWCentral Taiwan University of Science and Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the correlation between choroidal thickness and myopia progression using a deep learning method.

methodsTwo data sets, data set A and data set B, comprising of 123 optical coherence tomography (OCT) volumes, were collected to establish the model and verify its clinical utility. The proposed mask region-based convolutional neural network (R-CNN) model, trained with the pretrained weights from the Common Objects in Context database as well as the manually labeled OCT images from data set A, was used to automatically segment the choroid. To verify its clinical utility, the mask R-CNN model was tested with data set B, and the choroidal thickness estimated by the model was also used to explore its relationship with myopia.

resultsCompared with the result of manual segmentation in data set B, the error of the automatic choroidal inner and outer boundary segmentation was 6.72 ± 2.12 and 13.75 ± 7.57 µm, respectively. The mean dice coefficient between the region segmented by automatic and manual methods was 93.87% ± 2.89%. The mean difference in choroidal thickness over the Early Treatment Diabetic Retinopathy Study zone between the two methods was 10.52 µm. Additionally, the choroidal thickness estimated using the proposed model was thinner in high-myopic eyes, and axial length was the most significant predictor.

conclusionsThe mask R-CNN model has excellent performance in choroidal segmentation and quantification. In addition, the choroid of high myopia is significantly thinner than that of nonhigh myopia. TRANSLATIONAL RELEVANCE: This work lays the foundations for mask R-CNN models that could aid in the evaluation of more intricate changes occurring in chorioretinal diseases.

Indexed as

Deep LearningMyopiaArtificial IntelligenceChoroidHumansTomography, Optical Coherence

Identifiers

PMID35212716
PMCPMC8883159
OpenAlexW4214491511

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.