Evidence map›Paper›PMID 35212460›Full record

ReviewChemMedChem2022

Recent Developments in Porous Silicon Nanovectors with Various Imaging Modalities in the Framework of Theranostics.

Jing Qian, Huang Wen, Konstantin Tamarov, Wujun Xu, Vesa-Pekka Lehto

Abstract readReview
In one paragraph

Review in ChemMedChem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing QianDepartment of Applied Physics, University of Eastern Finland, Yliopistonranta 1, 70211, Kuopio, Finland.ORCID 0000-0002-7394-960X
Huang WenDepartment of Applied Physics, University of Eastern Finland, Yliopistonranta 1, 70211, Kuopio, Finland.
Konstantin TamarovDepartment of Applied Physics, University of Eastern Finland, Yliopistonranta 1, 70211, Kuopio, Finland.
Wujun XuDepartment of Applied Physics, University of Eastern Finland, Yliopistonranta 1, 70211, Kuopio, Finland.
Vesa-Pekka LehtoDepartment of Applied Physics, University of Eastern Finland, Yliopistonranta 1, 70211, Kuopio, Finland.ORCID 0000-0001-8153-1070

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of in vitro, ex vivo, and in vivo studies on porous silicon (PSi) nanoparticles for biomedical applications has increased extensively over the last decade. The focus of the reports has been on the carrier properties of PSi concerning the therapeutic aspect due to several beneficial nanovector characteristics including high payload capacity, biocompatibility, and versatile surface chemistry. Recently, increasing attention has been paid to the diagnostic aspects of PSi, which is typically attributed to the biotraceability of the nanovector. Also, PSi has been studied as a contrast agent. When both these aspects, therapy and diagnosis, are integrated into one nanovector, we can discuss a real nanotheranostics approach. Herein, we review the recent progress developing PSi for various imaging modalities, specifically focusing on optical imaging, magnetic resonance imaging, and nuclear medicine imaging. Furthermore, we summarized the knowledge gaps that must be covered before applying PSi in clinical imaging, highlighting future research trends.

Indexed as

NanoparticlesSiliconDrug Delivery SystemsPorosityPrecision MedicineSiliconbioimagingdrug deliverynanoparticlesPorous silicontheranostics

Identifiers

PMID35212460
PMCPMC9314675

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.