Evidence map›Paper›PMID 35212315›Full record

ReviewPathologica2022

Congenital anomalies of the tubular gastrointestinal tract.

Katrhin Ludwig, Debora De Bartolo, Angela Salerno, Giuseppe Ingravallo, Gerardo Cazzato, Cinzia Giacometti, Patrizia Dall'Igna

Open access · diamondAbstract readReview
In one paragraph

Review in Pathologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Katrhin LudwigDepartment of Pathology, Azienda Ospedale-Università Padova, Padua, Italy.
Debora De BartoloDepartment of Medicine, University of Padua School of Medicine, Padua, Italy.
Angela SalernoDepartment of Oncology, Anatomic and Histologic Pathology and Cytodiagnostics, Maggiore Hospital, Bologna, Italy.
Giuseppe IngravalloDepartment of Emergencies and Organ Transplantation, Section of Pathology, University of Bari, Bari, Italy.
Gerardo CazzatoDepartment of Emergencies and Organ Transplantation, Section of Pathology, University of Bari, Bari, Italy.
Cinzia GiacomettiDepartment of Services, Pathology Unit, ULSS 6 "Euganea", Camposampiero, Italy.
Patrizia Dall'IgnaDepartment of Emergencies and Organ Transplantation, Pediatric Surgery, University of Bari, Bari, Italy.
University of Bari Aldo Moro · ITOspedale Maggiore · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital anomalies of the tubular gastrointestinal tract are an important cause of morbidity not only in infants, but also in children and adults. The gastrointestinal (GI) tract, composed of all three primitive germ layers, develops early during embryogenesis. Two major steps in its development are the formation of the gut tube (giving rise to the foregut, the midgut and the hindgut), and the formation of individual organs with specialized cell types. Formation of an intact and functioning GI tract is under strict control from various molecular pathways. Disruption of any of these crucial mechanisms involved in the cell-fate decision along the dorsoventral, anteroposterior, left-right and radial axes, can lead to numerous congenital anomalies, most of which occur and present in infancy. However, they may run undetected during childhood. Therapy is surgical, which in some cases must be performed urgently, and prognosis depends on early diagnosis and suitable treatment. A precise pathologic macroscopic or microscopic diagnosis is important, not only for the immediate treatment and management of affected individuals, but also for future counselling of the affected individual and their family. This is even more true in cases of multiple anomalies or syndromic patterns. We discuss some of the more frequent or clinically important congenital anomalies of the tubular GI, including atresia's, duplications, intestinal malrotation, Meckel's diverticulum and Hirschsprung's Disease.

Indexed as

Digestive System AbnormalitiesIntestinal VolvulusMeckel DiverticulumHumansPrognosisgastrointestinal malformationsgastrointestinal tractHirschsprung Diseaseintestinal atresiaintestinal duplication

Identifiers

PMID35212315
PMCPMC9040549
OpenAlexW4214485305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.