ArticleJournal of internal medicine2022
Is acid suppression associated with the increased length of stay in diabetic ketoacidosis patients? A nationwide analysis.
Article in Journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Association of the Glasgow Coma Scale with the Length of Hospital Stay in Patients with Thyroid Storm.Internal medicine (Tokyo, Japan) · 2025Article
- Research Priorities for Diabetic Ketoacidosis: An Evidence and Gap Mapping Review.Medical sciences (Basel, Switzerland) · 2025Review
- Navigating Thyroid Crises: A Nationwide Analysis of the Weekend Effect and Mortality Trends in Myxedema Coma (2016-2020).Journal of community hospital internal medicine perspectives · 2025Article
- Diabetes Mellitus and the Risk and Outcomes ofInfection and drug resistance · 2025Review
- Impact of left ventricular assist devices on 30-day readmission and outcomes in non-variceal upper gastrointestinal bleeding: a nationwide analysis.Przeglad gastroenterologiczny · 2024Article
- Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis.Annals of medicine · 2023Article
- Is acid suppression associated with the increased length of stay in diabetic ketoacidosis patients? A nationwide analysis.Journal of internal medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic ketoacidosis (DKA) patients present with low serum bicarbonate (
objectivesWe aimed to introduce the hypothesis that DKA patients on acid-suppressive medications may have a delayed rise in serum
methodsThis is a retrospective study using Nationwide Inpatient Sample employing International Classification of Diseases (ICD-10) codes for adult patients with a primary diagnosis of DKA. Analyses were performed using STATA, proportions were compared using Fisher exact test, and continuous variables using Student's t-test. Confounding variables were adjusted using propensity matching, multivariate logistic, and linear regression analyses.
resultsDKA patients with PUD had higher adjusted LOS, intensive care unit admission, and total hospital costs. Mortality and morbidity indicators were similar in both groups. The variables found to be independent predictors of increased LOS were malnutrition, Clostridium difficile infection, pneumonia, Glasgow Coma Scale score of 3-8, and higher Charlson comorbidity score.
conclusionWe found that Clostridium difficile and pneumonia predicted longer LOS in DKA patients with concomitant PUD, hinting at the possible role of acid suppression in prolonging the LOS in such patients. However, further studies are needed to examine the effect of lesser
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