Evidence map›Paper›PMID 35212000›Full record

ArticleThe EMBO journal2022

Dermal αSMA

Kathleen M McAndrews, Toru Miyake, Ehsan A Ehsanipour, Patience J Kelly, Lisa M Becker, Daniel J McGrail, Hikaru Sugimoto, Valerie S LeBleu, Yejing Ge, Raghu Kalluri

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. DoesFrontiers in pharmacology · 2026
    Pooled it
  2. Fibroblasts in Scar Formation: Biology and Clinical Translation.Oxidative medicine and cellular longevity · 2022
    Pooled it
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  8. Marine-Derived Polyketides fromACS pharmacology & translational science · 2026
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  10. Loss of type III collagen has limited effect on tendon healing in young adult mice.Matrix biology : journal of the International Society for Matrix Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kathleen M McAndrews *Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-4092-4991
Toru Miyake *Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0003-0947-0116
Ehsan A Ehsanipour *Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Patience J KellyDepartment of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Lisa M BeckerDepartment of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Daniel J McGrailDepartment of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-6669-6069
Hikaru SugimotoDepartment of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Valerie S LeBleuDepartment of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yejing GeDepartment of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-2555-7900
Raghu KalluriDepartment of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-2190-547X
The University of Texas MD Anderson Cancer Center · USNorthwestern University · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Dissect stress response in skin epithelial wounding and hyperproliferative disordersK01AR072132 · NIAMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GE, YEJING · 2018 to 2022
$673k
Determining the Immunological Consequences of DNA Replication Stress Response Defects in Renal Cells Carcinoma to Improve Immunotherapy OutcomesK99CA240689 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MCGRAIL, DANIEL JAMES · 2019 to 2020
$207k
NCI NIH HHS K99 CA240689NCI NIH HHS P30 CA016672NIAMS NIH HHS K01 AR072132
6 · The paper itself

Abstract

Skin wound repair is essential for organismal survival and failure of which leads to non-healing wounds, a leading health issue worldwide. However, mechanistic understanding of chronic wounds remains a major challenge due to lack of appropriate genetic mouse models. αSMA

Indexed as

Collagen Type IMyofibroblastsWound HealingAnimalsFibroblastsIntegrin beta1MiceSkinCollagen Type IIntegrin beta1extracellular matrixmyofibroblastswound healing

Identifiers

PMID35212000
PMCPMC8982612
OpenAlexW4214726322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.