Evidence map›Paper›PMID 35211934›Full record

SynthesisRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2022

Deficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis.

Rosa Camila Lucchetta, Isabele Held Lemos, Ana Luísa Rodriguez Gini, Sophia de Andrade Cavicchioli, Marcela Forgerini, Fabiana Rossi Varallo, Mariane Nunes de Nadai, Fernando Fernandez-Llimos, Patricia de Carvalho Mastroianni

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Rosa Camila LucchettaDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, Universidade Estadual de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-4004-1320
Isabele Held LemosDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, Universidade Estadual de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0001-5493-8123
Ana Luísa Rodriguez GiniDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, Universidade Estadual de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0003-2643-810X
Sophia de Andrade CavicchioliUniversidade de Araraquara, Araraquara, São Paulo, SP, Brazil.ORCID 0000-0002-4922-4131
Marcela ForgeriniDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, Universidade Estadual de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-2905-8519
Fabiana Rossi VaralloDepartment of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.ORCID 0000-0003-4016-1442
Mariane Nunes de NadaiDepartment of Dentistry, Pediatric Dentistry and Public Health, Bauru School of Dentistry, Universidade de São Paulo, Bauru, SP, Brazil.ORCID 0000-0002-6706-7117
Fernando Fernandez-LlimosDepartment of Drug Sciences, Laboratory of Pharmacology, Faculty of Pharmacy, Universidade do Porto, Porto, Portugal.ORCID 0000-0002-8529-9595
Patricia de Carvalho MastroianniDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, Universidade Estadual de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0001-8467-7278
Universidade Estadual Paulista (Unesp) · BRCentro Universitário de Araraquara · BRUniversidade de Ribeirão Preto · BRUniversidade de São Paulo · BRUniversidade do Porto · PT

Funding

2018/07501-9 São Paulo Research Foundation (FAPESP)26/2019, process 4426122019-2 National Council for Scientific and Technological Development - CNPqFinance Code 001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES)
6 · The paper itself

Abstract

objectiveTo estimate the prevalence of inadequate vitamin D level and its associated factors for women of childbearing age in Brazil.

methodsA systematic review was conducted (last updated May 2020). Meta-analyses were performed using the inverse-variance for fixed models with summary proportion calculation by Freeman-Tukey double arcsine. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies.

resultsOur review identified 31 studies, comprising 4,006 participants. All the studies had at least one weakness, mainly due to the use of convenience sampling and small sample size. The overall prevalence of vitamin D deficiency, insufficiency, and both deficiency and insufficiency were 35% (confidence interval, 95%CI: 34-37%), 42% (95%CI: 41-44%), and 72% (95%CI: 71-74%), respectively.

conclusionAlthough the magnitude of the prevalence of inadequate levels of vitamin D is uncertain, the evidence suggests that presence of vitamin D deficiency or insufficiency in women of reproductive age can cause moderate to severe problems.

Indexed as

Vitamin DVitamin D DeficiencyBrazilFemaleHumansPrevalenceVitaminsVitamin DVitamins

Identifiers

PMID35211934
PMCPMC9948108
OpenAlexW4214683249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.