ArticleWorld journal of clinical cases2022
Comparison of diagnostic validity of two autism rating scales for suspected autism in a large Chinese sample.
Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Screening tools for autism in culturally and linguistically diverse paediatric populations: a systematic review.BMC pediatrics · 2024Pooled it
- Effects of a Nonwearable Digital Therapeutic Intervention on Preschoolers With Autism Spectrum Disorder in China: Open-Label Randomized Controlled Trial.Journal of medical Internet research · 2023Trial
- Association and predictive value of blood branched-chain and excitatory amino acids with autism spectrum disorder severity.BMC pediatrics · 2026Article
- Association of folate metabolism gene polymorphisms with autism susceptibility and symptom severity in the Chinese population.World journal of psychiatry · 2025Article
- Assessment of psychometric properties of autism spectrum diagnostic profile (ASDP) among Egyptian children aged 2-12 years.BMC psychiatry · 2025Article
- Therapeutic Effects of Electroencephalogram-Based Bioelectric Stimulation on Cognitive-Behavioural Outcomes in Children With Dual Diagnosis of Autism Spectrum Disorder and Intellectual Disability.Actas espanolas de psiquiatria · 2025Article
- Effects of ball combination training program combined with cTBS intervention on motor disorder in children with autism spectrum disorder.Scientific reports · 2025Article
- Investigating cerebral blood flow dysregulation and serum zinc correlation in 2-4 year-old children with autism spectrum disorder.European journal of medical research · 2025Article
- [Advances in research on gender differences in autism spectrum disorders].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Review
- Associations between amino acid levels and autism spectrum disorder severity.BMC psychiatry · 2025Article
- Comparison of the Clancy Autism Behavior Scale and Autism Behavior Checklist for Screening Autism Spectrum Disorder.Journal of autism and developmental disorders · 2025Article
- Recreational ball games are effective in improving social communication impairments among preschoolers diagnosed with autism spectrum disorder: a multi-arm controlled study.BMC sports science, medicine & rehabilitation · 2024Article
- Effects of transcutaneous auricular vagus nerve stimulation and exploration of brain network mechanisms in children with high-functioning autism spectrum disorder: study protocol for a randomized controlled trial.Frontiers in psychiatry · 2024Article
- Promoting playfulness through a play-based occupational therapy intervention: A study protocol.African journal of disability · 2024Article
- Improvement of symptoms in children with autism by TOMATIS training: a cross-sectional and longitudinal study.Frontiers in behavioral neuroscience · 2024Article
- Language Skill Differences Further Distinguish Social Sub-types in Children with Autism.Journal of autism and developmental disorders · 2024Article
- Effectiveness of peer-mediated intervention on social skills for children with autism spectrum disorder: a randomized controlled trial.Translational pediatrics · 2022Article
- Salivary oxytocin in autistic patients and in patients with intellectual disability.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutism is the most common clinical developmental disorder in children. The childhood autism rating scale (CARS) and autistic autism behavior checklist (ABC) are the most commonly used assessment scales for diagnosing autism. However, the diagnostic validations and the corresponding cutoffs for CARS and ABC in individuals with suspected autism spectrum disorder (ASD) remain unclear. Furthermore, for suspected ASD in China, it remains unclear whether CARS is a better diagnostic tool than ABC. Also unclear is whether the current cutoff points for ABC and CARS are suitable for the accurate diagnosis of ASD.
aimTo investigate the diagnostic validity of CARS and ABC based on a large Chinese sample.
methodsA total of 591 outpatient children from the ASD Unit at Beijing Children's Hospital between June and November 2019 were identified. First, the Clancy autism behavior scale (CABS) was used to screen out suspected autism from these children. Then, each suspected ASD was evaluated by CARS and ABC. Receiver operating characteristic (ROC) curve analysis was used to compare diagnostic validations. We also calculated the area under the curve (AUC) for both CARS and ABC.
resultsWe found that the Cronbach alpha coefficients of CARS and ABC were 0.772 and 0.426, respectively. Therefore, the reliability of the CARS was higher than that of the ABC. In addition, we found that the correlation between CARS and CABS was 0.732. Next, we performed ROC curve analysis for CARS and ABC, which yielded AUC values of 0.846 and 0.768, respectively. The cutoff value, which is associated with the maximum Youden index, is usually applied as a decision threshold. We found that the cutoff values of CARS and ABC were 34 and 67, respectively.
conclusionThis result indicated that CARS is superior to ABC in the Chinese population with suspected ASD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.