ArticleCurrent sleep medicine reports2021
Pathophysiology of Obstructive Sleep Apnea in Aging Women.
Article in Current sleep medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats.Experimental physiology · 2026Article
- Challenges for predicting oxygen response in OSA.American journal of respiratory and critical care medicine · 2026Article
- Gender differences in the psychosocial and functional impact of obstructive sleep apnea: findings from the SHINE patient survey.Sleep & breathing = Schlaf & Atmung · 2026Article
- Polysomnographic characteristics of excessive daytime sleepiness in postmenopausal women with obstructive sleep apnea.Frontiers in sleep · 2026Article
- Obstructive Sleep Apnea and Aging: A Narrative Review.Sleep medicine research · 2025Article
- Obstructive Sleep Apnea Syndrome in women: gender in sleep respiratory medicine is a first step towards personalized medicine.Sleep & breathing = Schlaf & Atmung · 2025Review
- Prevalence of high-risk group for obstructive sleep apnea using the STOP-Bang questionnaire and its association with cardiovascular morbidity.Frontiers in neurology · 2024Article
- The common link between sleep apnea syndrome and osteoarthritis: a literature review.Frontiers in medicine · 2024Review
- Article
- Metabolomic approach for obstructive sleep apnea in adults: a systematic review.Sleep and biological rhythms · 2023Review
- Menopause Is Associated with Obstructive Sleep Apnea in a Population-Based Sample from Mecklenburg-Western Pomerania, Germany.Journal of clinical medicine · 2023Article
- Change in the Constricted Airway in Patients after Clear Aligner Treatment: A Retrospective Study.Diagnostics (Basel, Switzerland) · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The following review is designed to explore the pathophysiology of sleep apnea in aging women. The review initially introduces four endotypes (i.e., a more collapsible airway, upper airway muscle responsiveness, arousal threshold, and loop gain) that may have a role in the initiation of obstructive sleep apnea. Thereafter, sex differences in the prevalence of sleep apnea are considered along with differences in the prevalence that exist between younger and older women. Following this discussion, we consider how each endotype might contribute to the increase in prevalence of sleep apnea in aging women. Lastly, we address how modifications in one form of respiratory plasticity, long-term facilitation, that might serve to mitigate apneic events in younger women may be modified in aging women with obstructive sleep apnea. Overall, the published literature indicates that the prevalence of sleep apnea is increased in aging women. This increase is linked primarily to a more collapsible airway and possibly to reduced responsiveness of upper airway muscle activity. In contrast, modifications in loop gain or the arousal threshold do not appear to have a role in the increased prevalence of sleep apnea in aging women. Moreover, we suggest that mitigation of long-term facilitation could contribute to the increased prevalence of sleep apnea in aging women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.