ArticleClinical kidney journal2022
Super high-flux membrane dialyzers improve mortality in patients on hemodialysis: a 3-year nationwide cohort study.
Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06989892 (Comparing Super High-flux and High-flux Dialyzer Performance Among Hemodialysis Patient With Sepsis), which is not on this map. Cited by 14 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparing Super High-flux and High-flux Dialyzer Performance Among Hemodialysis Patient With Sepsis : a Randomized Control Trial
Who cites it
14 citing papers in PubMed.
- Association of calcimimetic use with lower mortality in elderly patients with low body mass index and inflammation compared with non-users.Scientific reports · 2026Article
- Impact of high-flux vs. conventional hemodialysis on clinical efficacy in patients with chronic renal failure (uremic stage) using real-world data.American journal of translational research · 2026Article
- Lower mortality in calcimimetic users compared to non-users in dialysis patients with serum parathyroid hormone levels within the target range.Scientific reports · 2025Article
- Improved survival with high albumin leakage in patients with protein-energy wasting and inflammation on hemodialysis and online hemodiafiltration.Scientific reports · 2025Article
- The adequacy of vancomycin initial dosing in CRBSI for hemodialysis patients in a specialized district hospital of Malaysia.Innovations in pharmacy · 2025Article
- Management of Chronic Heart Failure in Dialysis Patients: A Challenging but Rewarding Path.Reviews in cardiovascular medicine · 2024Review
- Current dialyzer classification in Japan and mortality risk in patients undergoing hemodialysis.Scientific reports · 2024Article
- Latest Trends in Hemodiafiltration.Journal of clinical medicine · 2024Review
- Middle Molecular Uremic Toxin and Blood Purification Therapy.Journal of clinical medicine · 2024Review
- Albumin redox state of maintenance haemodialysis patients is positively altered after treatment.BMC nephrology · 2023Article
- Effectiveness of combination of heat water disinfection, continuous water circulation, and minimalized dead space for dialysis piping in maintaining ultrapure dialysis fluid and preventing biofilm formation in a central dialysis fluid delivery system.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2023Article
- High flux novel polymeric membrane for renal applications.Scientific reports · 2023Article
- Kinetics of Glucoregulatory Peptide Hormones during Hemodialysis with Cellulose Triacetate and Polysulfone Dialyzers in Patients with Diabetes and End-Stage Kidney Disease.International journal of molecular sciences · 2023Article
- Free Light Chains, High Mobility Group Box 1, and Mortality in Hemodialysis Patients.Journal of clinical medicine · 2022Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn Japan, dialyzers are classified based on β
methodsIn this nationwide prospective cohort study, we analyzed Japanese Society for Dialysis Therapy Renal Data Registry data collected at the end of 2008 and 2011. We enrolled 242,467 patients on maintenance hemodialysis and divided them into five groups by dialyzer type. We assessed the associations of each dialyzer type with 3-year all-cause mortality using Cox proportional hazards models and performed propensity score matching analysis, adjusting for potential confounders.
resultsBy the end of 2011, 53,172 (21.9%) prevalent dialysis patients had died. Mortality significantly decreased according to dialyzer type. Hazard ratios (HRs) were significantly higher for type I, II and III compared with type IV (reference) after adjustment for basic factors and further adjustment for dialysis-related factors. HR was significantly higher for type I, but significantly lower for type V, after further adjustment for nutrition- and inflammation-related factors. These significant findings were also evident after propensity score matching.
conclusionsHemodialysis using super high-flux dialyzers might reduce mortality. Randomized controlled trials are warranted to clarify whether these type V dialyzers can improve prognosis.
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